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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for methylcytosine dioxygenase activity
Gene ontology ID
GO:0070579
Definition
Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2
References
1. PMID 19372391
2. Reactome: R-HSA-5220952 "TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine"
3. Reactome: R-HSA-5220990 "TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine"
4. Reactome: R-HSA-5221014 "TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine"
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