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Gene ontology
Version 2014-12-22
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Details for phospholipase D-activating G protein-coupled receptor signaling pathway
Gene ontology ID
GO:0031583
Definition
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA)
Comment
This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase D (PLD) activation.
Synonyms
1. activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway
2. G-protein signalling, phospholipase D activating pathway
3. phospholipase D-activating G-protein coupled receptor signaling pathway
References
1. GOC: mah
2. GOC: signaling
3. PMID 11812783
4. PMID 15924269
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