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Gene ontology
Version 2014-12-22
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Details for somatostatin receptor signaling pathway
Gene ontology ID
GO:0038169
Definition
The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription
Comment
In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.
Synonyms
1. SST receptor signaling pathway
2. SSTR signaling pathway
References
1. GOC: jc
2. PMID 18006219
3. PMID 8769369
4. PR: 000001555
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