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Gene ontology
Version 2014-12-22
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Details for phospholipase C-activating G protein-coupled receptor signaling pathway
Gene ontology ID
GO:0007200
Definition
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG)
Comment
This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity.
Synonyms
1. activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
2. G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
3. G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
4. G-protein coupled receptor signaling pathway coupled to IP3 second messenger
5. G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
6. G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
7. phospholipase C-activating dopamine receptor signaling pathway
8. phospholipase C-activating G-protein coupled receptor signaling pathway
9. PLC-activating GPCR signaling pathway
References
1. GOC: dph
2. GOC: mah
3. GOC: signaling
4. GOC: tb
5. ISBN 0815316194
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