Gene ontology ID
GO:0043734
Definition
Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde
Synonyms
1. AlkB
2. alpha-ketoglutarate-dependent dioxygenase
References
1. PMID 197864992. Reactome: R-HSA-112118 "Oxidative demethylation of 1-meA damaged DNA by ALKBH2"
3. Reactome: R-HSA-112123 "Oxidative demethylation of 1-meA damaged DNA By ALKBH3"
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