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Gene ontology
Version 2014-12-22
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Details for sphingosine-1-phosphate receptor signaling pathway
Gene ontology ID
GO:0003376
Definition
A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription
Synonyms
1. S1P receptor signaling pathway
2. S1P signaling pathway
3. S1P-activated G-protein coupled receptor signaling pathway
4. S1P-activated GPCR signaling pathway
5. S1P-stimulated signal transduction pathway
6. sphingolipid signaling pathway
7. sphingolipid signalling pathway
References
1. GOC: ascb 2009
2. GOC: signaling
3. PMID 14592418
4. PMID 22001186
5. Reactome: R-HSA-419428
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