Gene ontology ID
GO:0004888
Definition
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction
Comment
This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.
Synonyms
1. transmembrane receptor activity
2. transmembrane signalling receptor activity
References
1. GOC: go curators
2. Wikipedia: Transmembrane receptor
3. Reactome: R-HSA-193672 "Sphingomyelinase is activated by the NGF:p75NTR complex"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA