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Gene ontology
Version 2014-12-22
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Details for G protein-coupled acetylcholine receptor signaling pathway
Gene ontology ID
GO:0007213
Definition
Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription
Synonyms
1. acetylcholine receptor signalling, muscarinic pathway
2. G-protein coupled acetylcholine receptor signaling pathway
3. muscarinic acetylcholine receptor signaling pathway
References
1. GOC: mah
2. ISBN 0815316194
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