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Information on EC 3.4.14.11 - Xaa-Pro dipeptidyl-peptidase

for references in articles please use BRENDA:EC3.4.14.11

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IUBMB Comments

The intracellular enzyme from Lactococcus lactis (190-kDa) is the type example of peptidase family S15. The reaction is similar to that catalysed by dipeptidyl-peptidase IV of animals

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
pepxp, x-prolyl dipeptidyl peptidase, prolyl dipeptidyl aminopeptidase, xaa-pro dipeptidyl-peptidase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Hydrolyses Xaa-Pro-/- bonds to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-/-p-nitroanilide and (sequentially) Tyr-Pro-/-Phe-Pro-/-Gly-Pro-/-Ile
show the reaction diagram
a member of peptidase family S15. The reaction is similar to that catalyzed by dipeptidyl-peptidase IV of animals
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