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Information on EC 3.2.1.33 - amylo-alpha-1,6-glucosidase

for references in articles please use BRENDA:EC3.2.1.33

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IUBMB Comments

This enzyme hydrolyses an unsubstituted glucose unit linked by an alpha(1->6) bond to an alpha(1->4) glucose chain. The enzyme activity found in mammals and yeast is in a polypeptide chain containing two active centres. The other activity is similar to that of EC 2.4.1.25 (4-alpha-glucanotransferase), which acts on the glycogen phosphorylase limit dextrin chains to expose the single glucose residues, which the 6-alpha-glucosidase activity can then hydrolyse. Together, these two activities constitute the glycogen debranching system.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
amylo-1,6-glucosidase, debrancher enzyme, amylo-alpha-1,6-glucosidase, debrancher protein, amylo-alpha-1,6-glucosidase activity, amylo-1,6-glucosidase/4-alpha-glucanotransferase, dextrin 6-glucohydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
6-O-alpha-D-glucosyl cyclomaltoheptaose + H2O = D-glucose + cyclomaltoheptaose
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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