Literature summary for 3.2.1.33 extracted from

Sottnik, J.L.; Mallaredy, V.; Chauca-Diaz, A.; Ritterson Lew, C.; Owens, C.; Dancik, G.M.; Pagliarani, S.; Lucchiari, S.; Moggio, M.; Ripolone, M.; Comi, G.P.; Frierson, H.F.; Clouthier, D.; Theodorescu, D.
Elucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice (2019), Carcinogenesis, 40, 194-201 .

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

General Information

General Information	Comment	Organism
malfunction	germline mutations lead to glycogen storage disease type III. Agl deletion increases the incidence of bladder cancer, supporting its role as a suppressor of transformation	Mus musculus
physiological function	the enzyme is primarily responsible for glycogen debranching. Agl deletion increases the incidence of bladder cancer, supporting its role as a suppressor of transformation	Mus musculus

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Release 2023.1 (January 2023)