Reference on EC 2.7.11.11 - cAMP-dependent protein kinase and Organism(s) Homo sapiens and UniProt Accession P22612
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Agustin, J.T.; Wilkerson, C.G.; Witman, G.B.
The unique catalytic subunit of sperm cAMP-dependent protein kinase is the product of an alternative Calpha mRNA expressed specifically in spermatogenic cells
Mol. Biol. Cell
11
3031-3044
2000
Homo sapiens (P17612), Homo sapiens
Desseyn, J.L.; Burton, K.A.; McKnight, G.S.
Expression of a nonmyristylated variant of the catalytic subunit of protein kinase A during male germ-cell development
Proc. Natl. Acad. Sci. USA
97
6433-6438
2000
Homo sapiens (P17612)
Maldonado, F.; Hanks, S.K.
A cDNA clone encoding human cAMP-dependent protein kinase catalytic subunit C alpha
Nucleic Acids Res.
16
8189-8190
1988
Homo sapiens (P17612), Homo sapiens
Beebe, S.J.; Oyen, O.; Sandberg, M.; Froysa, A.; Hansson, V.; Jahnsen, T.
Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase
Mol. Endocrinol.
4
465-475
1990
Homo sapiens (P22612), Homo sapiens (P22694), Homo sapiens
Reinton, N.; Haugen, T.B.; Orstavik, S.; Skalhegg, B.S.; Hansson, V.; Jahnsen, T.; Tasken, K.
The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon
Genomics
49
290-297
1998
Homo sapiens (P22612), Homo sapiens
Biondi, R.M.; Nebreda, A.R.
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions
Biochem. J.
372
1-13
2003
Homo sapiens
Soulsby, M.D.; Wojcikiewicz, R.J.H.
The type III inositol 1,4,5-trisphosphate receptor is phosphorylated by cAMP-dependent protein kinase at three sites
Biochem. J.
392
493-497
2005
Homo sapiens
Kuznetsov, A.; Uri, A.; Raidaru, G.; Jarv, J.
Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide-nucleoside conjugate AdcAhxArg6
Bioorg. Chem.
32
527-535
2004
Homo sapiens
Orstavik, S.; Funderud, A.; Hafte, T.T.; Eikvar, S.; Jahnsen, T.; Skalhegg, B.S.
Identification and characterization of novel PKA holoenzymes in human T lymphocytes
FEBS J.
272
1559-1567
2005
Homo sapiens
Rapacciuolo, A.; Suvarna, S.; Barki-Harrington, L.; Luttrell, L.M.; Cong, M.; Lefkowitz, R.J.; Rockman, H.A.
Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways
J. Biol. Chem.
278
35403-35411
2003
Homo sapiens
Piontek, J.; Brandt, R.
Differential and regulated binding of cAMP-dependent protein kinase and protein kinase C isoenzymes to gravin in human model neurons: evidence that gravin provides a dynamic platform for the localization of kinases during neuronal development
J. Biol. Chem.
278
38970-38979
2003
Homo sapiens
Sewer, M.B.; Waterman, M.R.
cAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells
J. Biol. Chem.
278
8106-8111
2003
Homo sapiens
Alfthan, K.; Heiska, L.; Gronholm, M.; Renkema, G.H.; Carpen, O.
Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization
J. Biol. Chem.
279
18559-18566
2004
Homo sapiens
Gardner, L.A.; Delos Santos, N.M.; Matta, S.G.; Whitt, M.A.; Bahouth, S.W.
Role of the cyclic AMP-dependent protein kinase in homologous resensitization of the beta1-adrenergic receptor
J. Biol. Chem.
279
21135-21143
2004
Homo sapiens
Viste, K.; Kopperud, R.K.; Christensen, A.E.; Doskeland, S.O.
Substrate enhances the sensitivity of type I protein kinase a to cAMP
J. Biol. Chem.
280
13279-13284
2005
Bos taurus, Homo sapiens
D'Souza, T.; Agarwal, R.; Morin, P.J.
Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells
J. Biol. Chem.
280
26233-26240
2005
Homo sapiens
Horner, T.J.; Osawa, S.; Schaller, M.D.; Weiss, E.R.
Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities
J. Biol. Chem.
280
28241-28250
2005
Bos taurus, Homo sapiens
Zhang, Y.; Li, H.L.; Wang, D.L.; Liu, S.J.; Wang, J.Z.
A transitory activation of protein kinase-A induces a sustained tau hyperphosphorylation at multiple sites in N2a cells-imply a new mechanism in Alzheimer pathology
J. Neural Transm.
2
1-11
2006
Homo sapiens
Lee, H.; Rezai-Zadeh, N.; Seto, E.
Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A
Mol. Cell. Biol.
24
765-773
2004
Homo sapiens
Tian, L.; Coghill, L.S.; McClafferty, H.; MacDonald, S.H.; Antoni, F.A.; Ruth, P.; Knaus, H.G.; Shipston, M.J.
Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase
Proc. Natl. Acad. Sci. USA
101
11897-11902
2004
Bos taurus, Homo sapiens
Howe, A.K.; Baldor, L.C.; Hogan, B.P.
Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration
Proc. Natl. Acad. Sci. USA
102
14320-14325
2005
Homo sapiens, Rattus norvegicus
Zhang, W.; Morris, G.Z.; Beebe, S.J.
Characterization of the cAMP-dependent protein kinase catalytic subunit Cgamma expressed and purified from sf9 cells
Protein Expr. Purif.
35
156-169
2004
Homo sapiens, Mus musculus
Conran, N.; Almeida, C.B.; Lanaro, C.; Ferreira, R.P.; Traina, F.; Saad, S.T.; Costa, F.F.
Inhibition of caspase-dependent spontaneous apoptosis via a cAMP-protein kinase A dependent pathway in neutrophils from sickle cell disease patients
Br. J. Haematol.
139
148-158
2007
Homo sapiens
Humphries, K.M.; Pennypacker, J.K.; Taylor, S.S.
Redox regulation of cAMP-dependent protein kinase signaling: kinase versus phosphatase inactivation
J. Biol. Chem.
282
22072-22079
2007
Homo sapiens
Borthwick, L.A.; McGaw, J.; Conner, G.; Taylor, C.J.; Gerke, V.; Mehta, A.; Robson, L.; Muimo, R.
The formation of the cAMP/protein kinase A-dependent annexin 2 S100A10 complex with cystic fibrosis conductance regulator protein (CFTR) regulates CFTR channel function
Mol. Biol. Cell
18
3388-3397
2007
Homo sapiens
Cheng, Y.; Zhang, Y.; McCammon, J.A.
How does activation loop phosphorylation modulate catalytic activity in the cAMP-dependent protein kinase: a theoretical study
Protein Sci.
15
672-683
2006
Homo sapiens
Shemetov, A.A.; Seit-Nebi, A.S.; Bukach, O.V.; Gusev, N.B.
Phosphorylation by cyclic AMP-dependent protein kinase inhibits chaperone-like activity of human HSP22 in vitro
Biochemistry
73
200-208
2008
Homo sapiens
Taylor, S.S.; Kim, C.; Cheng, C.Y.; Brown, S.H.; Wu, J.; Kannan, N.
Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design
Biochim. Biophys. Acta
1784
16-26
2008
Homo sapiens
Kleiveland, C.R.; Kassem, M.; Lea, T.
Human mesenchymal stem cell proliferation is regulated by PGE2 through differential activation of cAMP-dependent protein kinase isoforms
Exp. Cell Res.
314
1831-1838
2008
Homo sapiens
Larsen, A.C.; Kvissel, A.K.; Hafte, T.T.; Avellan, C.I.; Eikvar, S.; Rootwelt, T.; Orstavik, S.; Skalhegg, B.S.
Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates
FEBS J.
275
250-262
2008
Homo sapiens
Islam, A.; Jones, H.; Hiroi, T.; Lam, J.; Zhang, J.; Moss, J.; Vaughan, M.; Levine, S.J.
cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2
J. Biol. Chem.
283
25364-25371
2008
Homo sapiens
Dammer, E.B.; Sewer, M.B.
Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2
J. Biol. Chem.
283
6925-6934
2008
Homo sapiens
Chatelier, A.; Dahllund, L.; Eriksson, A.; Krupp, J.; Chahine, M.
Biophysical properties of human Na v1.7 splice variants and their regulation by protein kinase A
J. Neurophysiol.
99
2241-2250
2008
Homo sapiens
Farquhar, M.J.; Harris, H.J.; Diskar, M.; Jones, S.; Mee, C.J.; Nielsen, S.U.; Brimacombe, C.L.; Molina, S.; Toms, G.L.; Maurel, P.; Howl, J.; Herberg, F.W.; van Ijzendoorn, S.C.; Balfe, P.; McKeating, J.A.
Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity
J. Virol.
82
8797-8811
2008
Homo sapiens
Das, P.; Ezashi, T.; Gupta, R.; Roberts, R.M.
Combinatorial roles of protein kinase A, Ets2, and 3,5-cyclic-adenosine monophosphate response element-binding protein-binding protein/p300 in the transcriptional control of interferon-tau expression in a trophoblast cell line
Mol. Endocrinol.
22
331-343
2008
Homo sapiens
Dai, R.; Ali, M.K.; Lezcano, N.; Bergson, C.
A crucial role for cAMP and protein kinase A in D1 dopamine receptor regulated intracellular calcium transients
Neurosignals
16
112-123
2008
Homo sapiens, Rattus norvegicus
Desiniotis, A.; Schaefer, G.; Klocker, H.; Eder, I.E.
Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A
Int. J. Cancer
126
775-789
2010
Homo sapiens
Papa, S.; Scacco, S.; De Rasmo, D.; Signorile, A.; Papa, F.; Panelli, D.; Nicastro, A.; Scaringi, R.; Santeramo, A.; Roca, E.; Trentadue, R.; Larizza, M.
cAMP-dependent protein kinase regulates post-translational processing and expression of complex I subunits in mammalian cells
Biochim. Biophys. Acta
1797
649-658
2010
Homo sapiens, Mus musculus, Rattus norvegicus, Mus musculus BALB/c
Gerlits, O.; Waltman, M.J.; Taylor, S.; Langan, P.; Kovalevsky, A.
Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: an X-ray crystallographic study of complexes with various metals and peptide substrate SP20
Biochemistry
52
3721-3727
2013
Homo sapiens (P61925)
Huang, S.; Li, Q.; Alberts, I.; Li, X.
PRKX, a novel cAMP-dependent protein kinase member, plays an important role in development
J. Cell. Biochem.
117
566-573
2016
Homo sapiens (P17612), Homo sapiens
Komal, P.; Estakhr, J.; Kamran, M.; Renda, A.; Nashmi, R.
cAMP-dependent protein kinase inhibits alpha7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors
J. Physiol.
593
3513-3532
2015
Homo sapiens
Liu, Q.; Nguyen, E.; Doskeland, S.; Segal-Bendirdjian, E.
cAMP-dependent protein kinase A (PKA)-mediated c-Myc degradation is dependent on the relative proportion of PKA-I and PKA-II isozymes
Mol. Pharmacol.
88
469-476
2015
Homo sapiens
Sormus, T.; Lavogina, D.; Enkvist, E.; Uri, A.; Viht, K.
Efficient photocaging of a tight-binding bisubstrate inhibitor of cAMP-dependent protein kinase
Chem. Commun. (Camb.)
55
11147-11150
2019
Homo sapiens (P17612)
Luzi, N.M.; Lyons, C.E.; Peterson, D.L.; Ellis, K.C.
Kinetics and inhibition studies of the L205R mutant of cAMP-dependent protein kinase involved in Cushings syndrome
FEBS open bio
8
606-613
2018
Homo sapiens (P17612), Homo sapiens
Takahashi, M.; Li, Y.; Dillon, T.J.; Stork, P.J.
Phosphorylation of Rap1 by cAMP-dependent protein kinase (PKA) creates a binding site for KSR to sustain ERK activation by cAMP
J. Biol. Chem.
292
1449-1461
2017
Homo sapiens (P05132)
Madsen, A.; Bjune, J.; Bjorkhaug, L.; Mellgren, G.; Sagen, J.
The cAMP-dependent protein kinase downregulates glucose-6-phosphatase expression through RORalpha and SRC-2 coactivator transcriptional activity
Mol. Cell. Endocrinol.
419
92-101
2016
Homo sapiens (P17612)
Soberg, K.; Moen, L.V.; Skalhegg, B.S.; Laerdahl, J.K.
Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
PLoS ONE
12
e0181091
2017
Alligator mississippiensis, Gallus gallus, Anolis carolinensis, Callorhinchus milii, Aquila chrysaetos, Mus musculus (P05132), Mus musculus (P68181), Homo sapiens (P17612), Homo sapiens (P22694)
Walker-Gray, R.; Stengel, F.; Gold, M.G.
Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches
Proc. Natl. Acad. Sci. USA
114
10414-10419
2017
Homo sapiens (P22694), Homo sapiens, Rattus norvegicus (P27791), Rattus norvegicus Sprague-Dawley (P27791)
