Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-bromo-cAMP | activates | Homo sapiens | |
additional information | forskolin induces enzyme activity | Homo sapiens | |
prostaglandin E1 | activates | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + type III inositol 1,4,5-trisphosphate receptor | Homo sapiens | i.e. IP3 receptor, recombinantly expressed in HEK cells, forms tetrameric Ca2+ channels in the endoplasmic reticulum | ADP + phosphorylated type III inositol 1,4,5-trisphosphate receptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | embryonic kidney cell | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + type III inositol 1,4,5-trisphosphate receptor | i.e. IP3 receptor, recombinantly expressed in HEK cells, forms tetrameric Ca2+ channels in the endoplasmic reticulum | Homo sapiens | ADP + phosphorylated type III inositol 1,4,5-trisphosphate receptor | - |
? | |
ATP + type III inositol 1,4,5-trisphosphate receptor | phosphorylation sites are Ser916, Ser934, and Ser1832, Ser934 is the most susceptible site | Homo sapiens | ADP + phosphorylated type III inositol 1,4,5-trisphosphate receptor | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKA | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |