Reference on EC 2.7.10.2 - non-specific protein-tyrosine kinase and Organism(s) Mus musculus and UniProt Accession P05480
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Danio rerio (O12990), Danio rerio (O93596), Mus musculus (P00520), Mus musculus (Q9R117), Drosophila melanogaster (P00528), Drosophila melanogaster (P18106), Drosophila melanogaster (Q24145), Drosophila melanogaster (Q9V9J3), Homo sapiens (P06239), Homo sapiens (Q06187), Macaca fascicularis (Q95M30), Rattus norvegicus (Q9WUD9)
Chissoe, S.L.; Bodenteich, A.; Wang, Y.F.; Wang, Y.P.; Burian, D.; Clifton, S.W.; Crabtree, J.; Freeman, A.; Iyer, K.; Jian, L.; et al.
Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation
Genomics
27
67-82
1995
Homo sapiens (P00519), Mus musculus (P00520)
Bernards, A.; Paskind, M.; Baltimore, D.
Four murine c-abl mRNAs arise by usage of two transcriptional promoters and alternative splicing
Oncogene
2
297-304
1988
Mus musculus (P00520), Mus musculus
Musacchio, A.; Saraste, M.; Wilmanns, M.
High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides
Nat. Struct. Biol.
1
546-551
1994
Mus musculus (P00520), Homo sapiens (P06241)
Oppi, C.; Shore, S.K.; Reddy, E.P.
Nucleotide sequence of testis-derived c-abl cDNAs: implications for testis-specific transcription and abl oncogene activation
Proc. Natl. Acad. Sci. USA
84
8200-8204
1987
Mus musculus (P00520), Mus musculus
Wang, J.Y.; Ledley, F.; Goff, S.; Lee, R.; Groner, Y.; Baltimore, D.
The mouse c-abl locus: molecular cloning and characterization
Cell
36
349-356
1984
Mus musculus (P00520), Mus musculus
Martinez, R.; Mathey-Prevot, B.; Bernards, A.; Baltimore, D.
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart
Science
237
411-415
1987
Mus musculus (P05480)
Abraham, K.M.; Levin, S.D.; Marth, J.D.; Forbush, K.A.; Perlmutter, R.M.
Thymic tumorigenesis induced by overexpression of p56lck
Proc. Natl. Acad. Sci. USA
88
3977-3981
1991
Mus musculus (P06240), Mus musculus
Abraham, N.; Miceli, M.C.; Parnes, J.R.; Veillette, A.
Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck
Nature
350
62-66
1991
Mus musculus (P06240), Mus musculus
Benavente, J.; Shatkin, A.J.
Avian reovirus mRNAs are nonfunctional in infected mouse cells: translational basis for virus host-range restriction
Proc. Natl. Acad. Sci. USA
85
4257-4261
1988
Mus musculus (P06240)
Carrera, A.C.; Alexandrov, K.; Roberts, T.M.
The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP
Proc. Natl. Acad. Sci. USA
90
442-446
1993
Mus musculus (P06240)
Garvin, A.M.; Pawar, S.; Marth, J.D.; Perlmutter, R.M.
Structure of the murine lck gene and its rearrangement in a murine lymphoma cell line
Mol. Cell. Biol.
8
3058-3064
1988
Mus musculus (P06240), Mus musculus
Hurley, T.R.; Amrein, K.E.; Sefton, B.M.
Creation and characterization of temperature-sensitive mutants of the lck tyrosine protein kinase
J. Virol.
66
7406-7413
1992
Mus musculus (P06240)
Koegl, M.; Zlatkine, P.; Ley, S.C.; Courtneidge, S.A.; Magee, A.I.
Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif
Biochem. J.
303
749-753
1994
Mus musculus (P06240)
Marth, J.D.; Peet, R.; Krebs, E.G.; Perlmutter, R.M.
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
Cell
43
393-404
1985
Mus musculus (P06240), Mus musculus
Shenoy-Scaria, A.M.; Gauen, L.K.; Kwong, J.; Shaw, A.S.; Lublin, D.M.
Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins
Mol. Cell. Biol.
13
6385-6392
1993
Mus musculus (P06240)
Voronova, A.F.; Adler, H.T.; Sefton, B.M.
Two lck transcripts containing different 5' untranslated regions are present in T cells
Mol. Cell. Biol.
7
4407-4413
1987
Mus musculus (P06240), Mus musculus
Voronova, A.F.; Sefton, B.M.
Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion
Nature
319
682-685
1986
Mus musculus (P06240), Mus musculus
Holtzman, D.A.; Cook, W.D.; Dunn, A.R.
Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells
Proc. Natl. Acad. Sci. USA
84
8325-8329
1987
Mus musculus (P08103)
Klemsz, M.J.; McKercher, S.R.; Maki, R.A.
Nucleotide sequence of the mouse hck gene
Nucleic Acids Res.
15
9600
1987
Mus musculus (P08103)
Lock, P.; Ralph, S.; Stanley, E.; Boulet, I.; Ramsay, R.; Dunn, A.R.
Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization
Mol. Cell. Biol.
11
4363-4370
1991
Mus musculus (P08103), Homo sapiens (P08631)
King, F.J.; Cole, M.D.
Molecular cloning and sequencing of the murine c-fgr gene
Oncogene
5
337-344
1990
Mus musculus (P14234)
Yi, T.L.; Willman, C.L.
Cloning of the murine c-fgr proto-oncogene cDNA and induction of c-fgr expression by proliferation and activation factors in normal bone marrow-derived monocytic cells
Oncogene
4
1081-1087
1989
Mus musculus (P14234), Mus musculus
Wilks, A.F.; Kurban, R.R.; Hovens, C.M.; Ralph, S.J.
The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family
Gene
85
67-74
1989
Mus musculus (P16879), Mus musculus (P24604), Mus musculus (P25911), Mus musculus (P52332), Mus musculus (Q62120)
Dymecki, S.M.; Niederhuber, J.E.; Desiderio, S.V.
Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells
Science
247
332-336
1990
Mus musculus (P16277), Mus musculus
Metzler, W.J.; Leiting, B.; Pryor, K.; Mueller, L.; Farmer, B.T.
The three-dimensional solution structure of the SH2 domain from p55blk kinase
Biochemistry
35
6201-6211
1996
Mus musculus (P16277)
Wilks, A.F.; Kurban, R.R.
Isolation and structural analysis of murine c-fes cDNA clones
Oncogene
3
289-294
1988
Mus musculus (P16879), Mus musculus
Mano, H.; Ishikawa, F.; Nishida, J.; Hirai, H.; Takaku, F.
A novel protein-tyrosine kinase, tec, is preferentially expressed in liver
Oncogene
5
1781-1786
1990
Mus musculus (P24604), Mus musculus
Mano, H.; Mano, K.; Tang, B.; Koehler, M.; Yi, T.; Gilbert, D.J.; Jenkins, N.A.; Copeland, N.G.; Ihle, J.N.
Expression of a novel form of Tec kinase in hematopoietic cells and mapping of the gene to chromosome 5 near Kit
Oncogene
8
417-424
1993
Mus musculus (P24604), Mus musculus
Merkel, A.L.; Atmosukarto, II; Stevens, K.; Rathjen, P.D.; Booker, G.W.
Splice variants of the mouse Tec gene are differentially expressed in vivo
Cytogenet. Cell Genet.
84
132-139
1999
Mus musculus (P24604), Mus musculus
Stanley, E.; Ralph, S.; McEwen, S.; Boulet, I.; Holtzman, D.A.; Lock, P.; Dunn, A.R.
Alternatively spliced murine lyn mRNAs encode distinct proteins
Mol. Cell. Biol.
11
3399-3406
1991
Mus musculus (P25911)
Yi, T.L.; Bolen, J.B.; Ihle, J.N.
Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus
Mol. Cell. Biol.
11
2391-2398
1991
Mus musculus (P25911), Mus musculus
Oeltjen, J.C.; Liu, X.; Lu, J.; Allen, R.C.; Muzny, D.; Belmont, J.W.; Gibbs, R.A.
Sixty-nine kilobases of contiguous human genomic sequence containing the alpha-galactosidase A and Bruton's tyrosine kinase loci
Mamm. Genome
6
334-338
1995
Mus musculus (P35991)
Rawlings, D.J.; Saffran, D.C.; Tsukada, S.; Largaespada, D.A.; Grimaldi, J.C.; Cohen, L.; Mohr, R.N.; Bazan, J.F.; Howard, M.; Copeland, N.G.; et al.
Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
Science
261
358-361
1993
Mus musculus (P35991), Mus musculus
Sideras, P.; Muller, S.; Shiels, H.; Jin, H.; Khan, W.N.; Nilsson, L.; Parkinson, E.; Thomas, J.D.; Branden, L.; Larsson, I.; et al.
Genomic organization of mouse and human Bruton's agammaglobulinemia tyrosine kinase (Btk) loci
J. Immunol.
153
5607-5617
1994
Mus musculus (P35991), Mus musculus
Tsukada, S.; Saffran, D.C.; Rawlings, D.J.; Parolini, O.; Allen, R.C.; Klisak, I.; Sparkes, R.S.; Kubagawa, H.; Mohandas, T.; Quan, S.; et al.
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
Cell
72
279-290
1993
Mus musculus (P35991)
Yamada, N.; Kawakami, Y.; Kimura, H.; Fukamachi, H.; Baier, G.; Altman, A.; Kato, T.; Inagaki, Y.; Kawakami, T.
Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells
Biochem. Biophys. Res. Commun.
192
231-240
1993
Mus musculus (P35991), Mus musculus (Q03526)
Gilardi-Hebenstreit, P.; Nieto, M.A.; Frain, M.; Mattei, M.G.; Chestier, A.; Wilkinson, D.G.; Charnay, P.
An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain
Oncogene
7
2499-2506
1992
Mus musculus (P41241)
Klages, S.; Adam, D.; Class, K.; Fargnoli, J.; Bolen, J.B.; Penhallow, R.C.
Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family
Proc. Natl. Acad. Sci. USA
91
2597-2601
1994
Mus musculus (P41241), Mus musculus (P41242), Mus musculus
Chow, L.M.; Jarvis, C.; Hu, Q.; Nye, S.H.; Gervais, F.G.; Veillette, A.; Matis, L.A.
Ntk: a Csk-related protein-tyrosine kinase expressed in brain and T lymphocytes
Proc. Natl. Acad. Sci. USA
91
4975-4979
1994
Mus musculus (P41242)
Kaneko, Y.; Nonoguchi, K.; Fukuyama, H.; Takano, S.; Higashitsuji, H.; Nishiyama, H.; Takenawa, J.; Nakayama, H.; Fujita, J.
Presence of alternative 5' untranslated sequences and identification of cells expressing ctk transcripts in the brain and testis
Oncogene
10
945-952
1995
Mus musculus (P41242)
Haire, R.N.; Litman, G.W.
The murine form of TXK, a novel TEC kinase expressed in thymus maps to chromosome 5
Mamm. Genome
6
476-480
1995
Mus musculus (P42682), Mus musculus
Hu, Q.; Davidson, D.; Schwartzberg, P.L.; Macchiarini, F.; Lenardo, M.J.; Bluestone, J.A.; Matis, L.A.
Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage
J. Biol. Chem.
270
1928-1934
1995
Mus musculus (P42682)
Gauen, L.K.; Zhu, Y.; Letourneur, F.; Hu, Q.; Bolen, J.B.; Matis, L.A.; Klausner, R.D.; Shaw, A.S.
Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif
Mol. Cell. Biol.
14
3729-3741
1994
Mus musculus (P43404)
Fluck, M.; Zurcher, G.; Andres, A.C.; Ziemiecki, A.
Molecular characterization of the murine syk protein tyrosine kinase cDNA, transcripts and protein
Biochem. Biophys. Res. Commun.
213
273-281
1995
Mus musculus (P48025)
Turner, M.; Mee, P.J.; Costello, P.S.; Williams, O.; Price, A.A.; Duddy, L.P.; Furlong, M.T.; Geahlen, R.L.; Tybulewicz, V.L.
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
Nature
378
298-302
1995
Mus musculus (P48025)
Wilks, A.F.
Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction
Proc. Natl. Acad. Sci. USA
86
1603-1607
1989
Mus musculus (P52332), Mus musculus (Q62120)
Yang, X.; Chung, D.; Cepko, C.L.
Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system
J. Neurosci.
13
3006-3017
1993
Mus musculus (P52332), Mus musculus
Hebert, B.; Bergeron, J.; Tijssen, P.; Potworowski, E.F.
Protein tyrosine kinases transcribed in a murine thymic medullary epithelial cell line
Gene
143
257-260
1994
Mus musculus (Q04736)
Klages, S.; Adam, D.; Eiseman, E.; Fargnoli, J.; Dymecki, S.M.; Desiderio, S.V.; Bolen, J.B.
Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase
Oncogene
8
713-719
1993
Mus musculus (Q04736), Mus musculus
Silvennoinen, O.; Witthuhn, B.A.; Quelle, F.W.; Cleveland, J.L.; Yi, T.; Ihle, J.N.
Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction
Proc. Natl. Acad. Sci. USA
90
8429-8433
1993
Mus musculus (Q62120), Mus musculus
Gurniak, C.B.; Berg, L.J.
Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells
Blood
87
3151-3160
1996
Mus musculus (Q62137)
Rane, S.G.; Reddy, E.P.
JAK3: a novel JAK kinase associated with terminal differentiation of hematopoietic cells
Oncogene
9
2415-2423
1994
Mus musculus (Q62137)
Witthuhn, B.A.; Silvennoinen, O.; Miura, O.; Lai, K.S.; Cwik, C.; Liu, E.T.; Ihle, J.N.
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
Nature
370
153-157
1994
Mus musculus (Q62137)
Kawachi, Y.; Nakauchi, H.; Otsuka, F.
Isolation of a cDNA encoding a tyrosine kinase expressed in murine skin
Exp. Dermatol.
6
140-146
1997
Mus musculus (Q62270), Mus musculus
Kohmura, N.; Yagi, T.; Tomooka, Y.; Oyanagi, M.; Kominami, R.; Takeda, N.; Chiba, J.; Ikawa, Y.; Aizawa, S.
A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption
Mol. Cell. Biol.
14
6915-6925
1994
Mus musculus (Q62270)
Vasioukhin, V.; Serfas, M.S.; Siyanova, E.Y.; Polonskaia, M.; Costigan, V.J.; Liu, B.; Thomason, A.; Tyner, A.L.
A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract
Oncogene
10
349-357
1995
Mus musculus (Q64434), Mus musculus
Benzing, T.; Gerke, P.; Hopker, K.; Hildebrandt, F.; Kim, E.; Walz, G.
Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2
Proc. Natl. Acad. Sci. USA
98
9784-9789
2001
Mus musculus (Q9QVP9)
Burgaya, F.; Toutant, M.; Studler, J.M.; Costa, A.; Le Bert, M.; Gelman, M.; Girault, J.A.
Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activity
J. Biol. Chem.
272
28720-28725
1997
Mus musculus (P34152)
Avraham, S.; London, R.; Fu, Y.; Ota, S.; Hiregowdara, D.; Li, J.; Jiang, S.; Pasztor, L.M.; White, R.A.; Groopman, J.E.; et al.
Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain
J. Biol. Chem.
270
27742-27751
1995
Mus musculus (Q9QVP9), Mus musculus
Hanks, S.K.; Calab, M.B.; Harper, M.C.; Patel, S.K.
Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin
Proc. Natl. Acad. Sci. USA
89
8487-8491
1992
Mus musculus (P34152), Mus musculus
Kawai, J.; Shinagawa, A.; Shibata, K.; Yoshino, M.; Itoh, M.; et al.
Functional annotation of a full-length mouse cDNA collection
Nature
409
685-690
2001
Mus musculus (P04627), Mus musculus (P47810)
Greenwald, J.; Fischer, W.H.; Vale, W.W.; Choe, S.
Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase
Nat. Struct. Biol.
6
18-22
1999
Mus musculus (P27038)
Beppu, H.; Minowa, O.; Miyazono, K.; Kawabata, M.
cDNA cloning and genomic organization of the mouse BMP type II receptor
Biochem. Biophys. Res. Commun.
235
499-504
1997
Mus musculus (O35607), Mus musculus
Wu, X.; Robinson, C.E.; Fong, H.W.; Crabtree, J.S.; Rodriguez, B.R.; Roe, B.A.; Gimble, J.M.
Cloning and characterization of the murine activin receptor like kinase-1 (ALK-1) homolog
Biochem. Biophys. Res. Commun.
216
78-83
1995
Mus musculus (Q61288)
Dewulf, N.; Verschueren, K.; Lonnoy, O.; Moren, A.; Grimsby, S.; Vande Spiegle, K.; Miyazono, K.; Huylebroeck, D.; Ten Dijke, P.
Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis
Endocrinology
136
2652-2663
1995
Mus musculus (P36895), Mus musculus (Q61288)
Tomoda, T.; Kudoh, T.; Noma, T.; Nakazawa, A.; Muramatsu, M.; Arai, K.
Molecular cloning of a mouse counterpart for human TGF-beta type I receptor
Biochem. Biophys. Res. Commun.
198
1054-1062
1994
Mus musculus (Q64729)
ten Dijke, P.; Yamashita, H.; Ichijo, H.; Franzen, P.; Laiho, M.; Miyazono, K.; Heldin, C.H.
Characterization of type I receptors for transforming growth factor-beta and activin
Science
264
101-104
1994
Mus musculus (P36898)
Suzuki, A.; Shioda, N.; Maeda, T.; Tada, M.; Ueno, N.
Cloning of an isoform of mouse TGF-beta type II receptor gene
FEBS Lett.
355
19-22
1994
Mus musculus (Q62312), Mus musculus
Suzuki, A.; Thies, R.S.; Yamaji, N.; Song, J.J.; Wozney, J.M.; Murakami, K.; Ueno, N.
A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo
Proc. Natl. Acad. Sci. USA
91
10255-10259
1994
Mus musculus (P36895)
Suzuki, A.; Shioda, N.; Maeda, T.; Tada, M.; Ueno, N.
A mouse TGF-beta type I receptor that requires type II receptor for ligand binding
Biochem. Biophys. Res. Commun.
198
1063-1069
1994
Mus musculus (Q64729), Mus musculus
Lawler, S.; Candia, A.F.; Ebner, R.; Shum, L.; Lopez, A.R.; Moses, H.L.; Wright, C.V.; Derynck, R.
The murine type II TGF-beta receptor has a coincident embryonic expression and binding preference for TGF-beta 1
Development
120
165-175
1994
Mus musculus (Q62312)
Koenig, B.B.; Cook, J.S.; Wolsing, D.H.; Ting, J.; Tiesman, J.P.; Correa, P.E.; Olson, C.A.; Pecquet, A.L.; Ventura, F.; Grant, R.A.; et, a.
Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells
Mol. Cell. Biol.
14
5961-5974
1994
Mus musculus (P36895), Mus musculus
ten Dijke, P.; Ichijo, H.; Franzen, P.; Schulz, P.; Saras, J.; Toyoshima, H.; Heldin, C.H.; Miyazono, K.
Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity
Oncogene
8
2879-2887
1993
Homo sapiens (P36894), Homo sapiens (P37023), Homo sapiens (Q04771), Homo sapiens, Mus musculus (P36898)
Ebner, R.; Chen, R.H.; Shum, L.; Lawler, S.; Zioncheck, T.F.; Lee, A.; Lopez, A.R.; Derynck, R.
Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor
Science
260
1344-1348
1993
Mus musculus (P37172)
Attisano, L.; Wrana, J.L.; Cheifetz, S.; Massague, J.
Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
Cell
68
97-108
1992
Mus musculus (P27040)
Mathews, L.S.; Vale, W.W.
Expression cloning of an activin receptor, a predicted transmembrane serine kinase
Cell
65
973-982
1991
Mus musculus (P27038)
Rechavi, G.; Givol, D.; Canaani, E.
Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element
Nature
300
607-611
1982
Mus musculus (P00536)
Van Beveren, C.; van Straaten, F.; Galleshaw, J.A.; Verma, I.M.
Nucleotide sequence of the genome of a murine sarcoma virus
Cell
27
97-108
1981
Mus musculus (P00536), Moloney murine sarcoma virus (P00538)
Li, F.; Liu, J.; Mayne, R.; Wu, C.
Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase
Biochim. Biophys. Acta
1358
215-220
1997
Homo sapiens (Q13418), Mus musculus (O55222)
Toshima, J.; Nakagawara, K.; Mori, M.; Noda, T.; Mizuno, K.
Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene
Gene
206
237-245
1998
Mus musculus (O70146), Mus musculus
Trofimova, M.; Sprenkle, A.B.; Green, M.; Sturgill, T.W.; Goebl, M.G.; Harrington, M.A.
Developmental and tissue-specific expression of mouse pelle-like protein kinase
J. Biol. Chem.
271
17609-17612
1996
Mus musculus (Q62406)
Stanger, B.Z.; Leder, P.; Lee, T.H.; Kim, E.; Seed, B.
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
Cell
81
513-523
1995
Homo sapiens (Q13546), Mus musculus (Q60855)
Pazdernik, N.J.; Donner, D.B.; Goebl, M.G.; Harrington, M.A.
Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-kappaB
Mol. Cell. Biol.
19
6500-6508
1999
Mus musculus (Q9QZl0), Mus musculus
Honda, R.; Ohba, Y.; Yasuda, H.
14-3-3 Zeta protein binds to the carboxyl half of mouse wee1 kinase
Biochem. Biophys. Res. Commun.
230
262-265
1997
Mus musculus (P47810)
Honda, R.; Tanaka, H.; Ohba, Y.; Yasuda, H.
Mouse p87wee1 kinase is regulated by M-phase specific phosphorylation
Chromosome Res.
3
300-308
1995
Mus musculus (P47810)
Anastasiadou, E.; Schwaller, J.
Role of constitutively activated protein tyrosine kinases in malignant myeloproliferative disorders: an update
Curr. Opin. Hematol.
10
40-48
2003
Homo sapiens, Mus musculus
Senis, Y.A.; Craig, A.W.; Greer, P.A.
Fps/Fes and Fer protein-tyrosine kinases play redundant roles in regulating hematopoiesis
Exp. Hematol.
31
673-681
2003
Mus musculus
Sangrar, W.; Gao, Y.; Bates, B.; Zirngibl, R.; Greer, P.A.
Activated Fps/Fes tyrosine kinase regulates erythroid differentiation and survival
Exp. Hematol.
32
935-945
2004
Mus musculus
Law, S.; Maiti, D.; Palit, A.; Chaudhuri, S.
Role of biomodulators and involvement of protein tyrosine kinase on stem cell migration in normal and leukaemic mice
Immunol. Lett.
86
287-290
2003
Mus musculus
Gevrey, J.C.; Isaac, B.M.; Cox, D.
Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine)
J. Immunol.
175
3737-3745
2005
Mus musculus
Arnaud, L.; Ballif, B.A.; Cooper, J.A.
Regulation of protein tyrosine kinase signaling by substrate degradation during brain development
Mol. Cell. Biol.
23
9293-9302
2003
Mus musculus, Mus musculus C57BL6J/129Sv
Meyn, M.A., 3rd; Schreiner, S.J.; Dumitrescu, T.P.; Nau, G.J.; Smithgall, T.E.
Src family kinase activity is required for murine embryonic stem cell growth and differentiation
Mol. Pharmacol.
68
1320-1330
2005
Mus musculus
Okutani, D.; Lodyga, M.; Han, B.; Liu, M.
Src protein tyrosine kinase family and acute inflammatory responses
Am. J. Physiol. Lung Cell Mol. Physiol.
291
L129-L141
2006
Homo sapiens, Mus musculus, Rattus norvegicus
Wallace, T.A.; Sayeski, P.P.
Jak2 tyrosine kinase: a mediator of both housekeeping and ligand-dependent gene expression?
Cell Biochem. Biophys.
44
213-222
2006
Drosophila melanogaster, Homo sapiens, Mus musculus
Matsui, A.; Okigaki, M.; Amano, K.; Adachi, Y.; Jin, D.; Takai, S.; Yamashita, T.; Kawashima, S.; Kurihara, T.; Miyazaki, M.; Tateishi, K.; Matsunaga, S.; Katsume, A.; Honshou, S.; Takahashi, T.; Matoba, S.; Kusaba, T.; Tatsumi, T.; Matsubara, H.
Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function
Circulation
116
1041-1051
2007
Mus musculus
Angelucci, A.; Bologna, M.
Targeting vascular cell migration as a strategy for blocking angiogenesis: the central role of focal adhesion protein tyrosine kinase family
Curr. Pharm. Des.
13
2129-2145
2007
Homo sapiens, Mus musculus
Ortolano, S.; Hwang, I.Y.; Han, S.B.; Kehrl, J.H.
Roles for phosphoinositide 3-kinases, Brutons tyrosine kinase, and Jun kinases in B lymphocyte chemotaxis and homing
Eur. J. Immunol.
36
1285-1295
2006
Homo sapiens, Mus musculus
Frenzel, K.; Wallace, T.A.; McDoom, I.; Xiao, H.D.; Capecchi, M.R.; Bernstein, K.E.; Sayeski, P.P.
A functional Jak2 tyrosine kinase domain is essential for mouse development
Exp. Cell Res.
312
2735-2744
2006
Mus musculus (Q62120), Mus musculus
Zarbock, A.; Lowell, C.A.; Ley, K.
Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1
Immunity
26
773-783
2007
Mus musculus
McGarrigle, D.; Shan, D.; Yang, S.; Huang, X.Y.
Role of tyrosine kinase Csk in G protein-coupled receptor- and receptor tyrosine kinase-induced fibroblast cell migration
J. Biol. Chem.
281
10583-10588
2006
Mus musculus
Schmidt, N.W.; Thieu, V.T.; Mann, B.A.; Ahyi, A.N.; Kaplan, M.H.
Brutons tyrosine kinase is required for TLR-induced IL-10 production
J. Immunol.
177
7203-7210
2006
Mus musculus, Mus musculus C57BL/6
Gururajan, M.; Dasu, T.; Shahidain, S.; Jennings, C.D.; Robertson, D.A.; Rangnekar, V.M.; Bondada, S.
Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth
J. Immunol.
178
111-121
2007
Homo sapiens, Mus musculus
Pereira, D.B.; Chao, M.V.
The tyrosine kinase Fyn determines the localization of TrkB receptors in lipid rafts
J. Neurosci.
27
4859-4869
2007
Mus musculus, Rattus norvegicus
Sirvent, A.; Boureux, A.; Simon, V.; Leroy, C.; Roche, S.
The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells
Oncogene
26
7313-7323
2007
Homo sapiens, Mus musculus
Li, C.H.; Zhang, Q.; Teng, B.; Mustafa, S.J.; Huang, J.Y.; Yu, H.G.
Src tyrosine kinase alters gating of hyperpolarization-activated HCN4 pacemaker channel through Tyr531
Am. J. Physiol. Cell Physiol.
294
C355-C362
2008
Mus musculus, Homo sapiens (P12931)
Yin, H.; Liu, J.; Li, Z.; Berndt, M.C.; Lowell, C.A.; Du, X.
Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway
Blood
112
1139-1146
2008
Mus musculus (P25911)
Shinohara, M.; Koga, T.; Okamoto, K.; Sakaguchi, S.; Arai, K.; Yasuda, H.; Takai, T.; Kodama, T.; Morio, T.; Geha, R.S.; Kitamura, D.; Kurosaki, T.; Ellmeier, W.; Takayanagi, H.
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals
Cell
132
794-806
2008
Mus musculus (P24604), Mus musculus (P35991)
Tsuda, M.; Tozaki-Saitoh, H.; Masuda, T.; Toyomitsu, E.; Tezuka, T.; Yamamoto, T.; Inoue, K.
Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury
Glia
56
50-58
2008
Mus musculus (P25911), Rattus norvegicus (Q07014)
Lee, Y.G.; Chain, B.M.; Cho, J.Y.
Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of kappaBalpha via activation of the phosphoinositide-3-kinase and Akt pathways
Int. J. Biochem. Cell Biol.
41
811-821
2009
Mus musculus (P48025)
Lee, K.G.; Xu, S.; Wong, E.T.; Tergaonkar, V.; Lam, K.P.
Brutons tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B Cells
J. Biol. Chem.
283
11189-11198
2008
Mus musculus
Lee, S.H.; Kim, T.; Jeong, D.; Kim, N.; Choi, Y.
The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation
J. Biol. Chem.
283
11526-11534
2008
Mus musculus
Williams, N.K.; Lucet, I.S.; Klinken, S.P.; Ingley, E.; Rossjohn, J.
Crystal structures of the Lyn protein tyrosine kinase domain in its apo- and inhibitor-bound state
J. Biol. Chem.
284
284-291
2009
Mus musculus
Jongstra-Bilen, J.; Puig Cano, A.; Hasija, M.; Xiao, H.; Smith, C.I.; Cybulsky, M.I.
Dual functions of Brutons tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis
J. Immunol.
181
288-298
2008
Mus musculus, Mus musculus (P24604)
Jelacic, T.M.; Thompson, D.; Hanson, C.; Cmarik, J.L.; Nishigaki, K.; Ruscetti, S.
The tyrosine kinase sf-Stk and its downstream signals are required for maintenance of friend spleen focus-forming virus-induced fibroblast transformation
J. Virol.
82
419-427
2008
Mus musculus
MacPartlin, M.; Smith, A.M.; Druker, B.J.; Honigberg, L.A.; Deininger, M.W.
Brutons tyrosine kinase is not essential for Bcr-Abl-mediated transformation of lymphoid or myeloid cells
Leukemia
22
1354-1360
2008
Mus musculus
Chaturvedi, G.; Arai, K.; Terranova, P.F.; Roby, K.F.
The Src tyrosine kinase pathway regulates thecal CYP17 expression and androstenedione secretion
Mol. Cell. Biochem.
318
191-200
2008
Mus musculus
Parsa, K.V.; Butchar, J.P.; Rajaram, M.V.; Cremer, T.J.; Tridandapani, S.
The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk
Mol. Immunol.
45
3012-3021
2008
Mus musculus, Homo sapiens (P43405)
Furuhata, A.; Kimura, A.; Shide, K.; Shimoda, K.; Murakami, M.; Ito, H.; Gao, S.; Yoshida, K.; Tagawa, Y.; Hagiwara, K.; Takagi, A.; Kojima, T.; Suzuki, M.; Abe, A.; Naoe, T.; Murate, T.
p27 deregulation by Skp2 overexpression induced by the JAK2V617 mutation
Biochem. Biophys. Res. Commun.
383
411-416
2009
Mus musculus (Q62120)
Pesu, M.; Laurence, A.; Kishore, N.; Zwillich, S.H.; Chan, G.; OShea, J.J.
Therapeutic targeting of Janus kinases
Immunol. Rev.
223
132-142
2008
Homo sapiens, Mus musculus
Ghoreschi, K.; Laurence, A.; OShea, J.J.
Janus kinases in immune cell signaling
Immunol. Rev.
228
273-287
2009
Homo sapiens, Mus musculus
Walz, C.; Cross, N.C.; Van Etten, R.A.; Reiter, A.
Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders
Leukemia
22
1320-1334
2008
Homo sapiens, Mus musculus
Kim, E.J.; Monje, F.J.; Li, L.; Hoeger, H.; Pollak, D.D.; Lubec, G.
Alzheimer's disease risk factor lymphocyte-specific protein tyrosine kinase regulates long-term synaptic strengthening, spatial learning and memory
Cell. Mol. Life Sci.
70
743-759
2013
Mus musculus
Bao, Y.; Zheng, J.; Han, C.; Jin, J.; Han, H.; Liu, Y.; Lau, Y.; Tu, W.; Cao, X.
Tyrosine kinase Btk is required for NK cell activation
J. Biol. Chem.
287
23769-23778
2012
Mus musculus (P35991), Mus musculus, Homo sapiens (Q06187), Homo sapiens
Lin, Y.L.; Roux, B.
Computational analysis of the binding specificity of Gleevec to Abl, c-Kit, Lck, and c-Src tyrosine kinases
J. Am. Chem. Soc.
135
14741-14753
2013
Mus musculus (P00520), Gallus gallus (P00523), Homo sapiens (P06239)
Nuendel, K.; Busto, P.; Debatis, M.; Marshak-Rothstein, A.
The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells
J. Leukoc. Biol.
94
865-875
2013
Mus musculus (P35991)
De Lucca, G.; Shi, Q.; Liu, Q.; Batt, D.; Beaudoin Bertrand, M.; Rampulla, R.; Mathur, A.; Discenza, L.; DArienzo, C.; Dai, J.; Obermeier, M.; Vickery, R.; Zhang, Y.; Yang, Z.; Marathe, P.; Tebben, A.; Muckelbauer, J.; Chang, C.; Zhang, H.; Gillooly, K.;
Small molecule reversible inhibitors of Bruton's tyrosine kinase (BTK): structure-activity relationships leading to the identification of 7-(2-hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)
J. Med. Chem.
59
7915-7935
2016
Mus musculus (P35991)
Francis, K.R.; Wei, L.; Yu, S.P.
Src tyrosine kinases regulate neuronal differentiation of mouse embryonic stem cells via modulation of voltage-gated sodium channel activity
Neurochem. Res.
40
674-687
2015
Mus musculus
Dasari, T.; Geiger, R.; Karki, R.; Banoth, B.; Sharma, B.; Gurung, P.; Burton, A.; Kanneganti, T.
The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis
J. Biol. Chem.
295
3394-3400
2020
Homo sapiens (P43405), Homo sapiens, Mus musculus (P48025), Mus musculus
