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Literature summary for 2.7.10.2 extracted from

  • Turner, M.; Mee, P.J.; Costello, P.S.; Williams, O.; Price, A.A.; Duddy, L.P.; Furlong, M.T.; Geahlen, R.L.; Tybulewicz, V.L.
    Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk (1995), Nature, 378, 298-302.
    View publication on PubMed
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
72000
-
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Syk-deficient radiation chimaeras fail to accumulate mature B cells, Syk-deficient mice show impaired development of thymocytes using the V gamma 3 variable region gene, Syk is not required for signalling through the IL-2 and G-CSF receptors ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P48025
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hematopoietic cell
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 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Syk-deficient radiation chimaeras fail to accumulate mature B cells, Syk-deficient mice show impaired development of thymocytes using the V gamma 3 variable region gene, Syk is not required for signalling through the IL-2 and G-CSF receptors Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
tyrosine-protein kinase SYK
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 Mus musculus