Literature summary for 2.7.10.2 extracted from

Law, S.; Maiti, D.; Palit, A.; Chaudhuri, S.
Role of biomodulators and involvement of protein tyrosine kinase on stem cell migration in normal and leukaemic mice (2003), Immunol. Lett., 86, 287-290.

Search for more literature for 2.7.10.2

Activating Compound

Activating Compound	Comment	Organism	Structure
interleukin-2	enzyme activation in leukemic bone marrow cells	Mus musculus
additional information	a treatment of leukemic bone marrow cells with a mixture of interleukin-2, interferon-gamma, and non-specific BRM sheep erythrocytes leads to an increase in enzyme activity	Mus musculus
N,N'-ethylnitrosourea	enzyme activation in leukemic bone marrow cells	Mus musculus
non-specific BRM sheep erythrocyte	BRM is biological response modifier, treatment leads to a slight enzyme activation in leukemic bone marrow cells	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
interferon-gamma	enzyme inhibition in leukemic bone marrow cells	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Mus musculus	5829	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	the enzyme plays an important role in the self-renewal and as comitogen in the movement of stem cells out of the haematopoietic stem cell pool into the progeny pool, regulation of bone marrow cell migration	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	female and male Swiss albino mice	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bone marrow	pluripotent cells of healthy and leukemic mice	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme plays an important role in the self-renewal and as comitogen in the movement of stem cells out of the haematopoietic stem cell pool into the progeny pool, regulation of bone marrow cell migration	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
Protein tyrosine kinase	-	Mus musculus
PTK	-	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)