5.3.99.5: thromboxane-A synthase
This is an abbreviated version!
For detailed information about thromboxane-A synthase, go to the full flat file.
Word Map on EC 5.3.99.5
-
5.3.99.5
-
platelet
-
prostaglandin
-
arachidonic
-
artery
-
cyclooxygenase
-
prostacyclin
-
indomethacin
-
endothelial
-
endoperoxide
-
pulmonary
-
prostanoids
-
aspirin
-
dazoxiben
-
coronary
-
eicosanoids
-
vasoconstrictor
-
leukotriene
-
imidazole
-
hypertension
-
thrombosis
-
aorta
-
hemodynamic
-
antiplatelet
-
6-keto-pgf1
-
cox-2
-
5-lipoxygenase
-
6-keto-prostaglandin
-
vasodilator
-
antithrombotic
-
ozagrel
-
endothelium-dependent
-
thrombus
-
paf
-
endothelium-derived
-
bronchoconstriction
-
6-keto
-
platelet-rich
-
constrictor
-
collagen-induced
-
aa-induced
-
analysis
-
medicine
-
aspirin-treated
-
pharmacology
-
ticlopidine
-
reocclusion
-
meclofenamate
-
f1alpha
-
pgg2
-
iloprost
-
antiaggregatory
-
14c-arachidonic
-
proaggregatory
- 5.3.99.5
- platelet
- prostaglandin
-
arachidonic
- artery
-
cyclooxygenase
- prostacyclin
- indomethacin
- endothelial
-
endoperoxide
- pulmonary
-
prostanoids
- aspirin
- dazoxiben
- coronary
-
eicosanoids
-
vasoconstrictor
-
leukotriene
- imidazole
- hypertension
- thrombosis
- aorta
-
hemodynamic
-
antiplatelet
-
6-keto-pgf1
- cox-2
-
5-lipoxygenase
-
6-keto-prostaglandin
-
vasodilator
-
antithrombotic
- ozagrel
-
endothelium-dependent
- thrombus
- paf
-
endothelium-derived
-
bronchoconstriction
-
6-keto
-
platelet-rich
-
constrictor
-
collagen-induced
-
aa-induced
- analysis
- medicine
-
aspirin-treated
- pharmacology
- ticlopidine
-
reocclusion
- meclofenamate
-
f1alpha
- pgg2
-
iloprost
-
antiaggregatory
-
14c-arachidonic
-
proaggregatory
Reaction
Synonyms
CYP5A1, Synthetase, thromboxane, TBXAS1, Thromboxan synthetase, thromboxane A synthase 1, thromboxane A-synthase, thromboxane A2 synthase, thromboxane A2 synthase 1, Thromboxane A2 synthetase, thromboxane synthase, Thromboxane synthetase, TXA synthase, TxA-synthase, TXA2 synthase, TXAS, TXS, TXSA, TxSI
ECTree
Advanced search results
Application
Application on EC 5.3.99.5 - thromboxane-A synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
analysis
medicine
pharmacology
-
application of monoclonal antibodies to develop a tandem immunoradiometric assay
analysis
-
immobilized enzyme is sufficiently stable to be used as a model for studying the properties of the enzyme
-
the thromboxane A2 synthetase inhibitor/thromboxane A2-receptor antagonist (5Z)-6-[(2S,4R)-4-(4-chlorophenylsulfonylamino)-1-(3-pyridylmethyl)-2-pyrrolidinyl]-5-hexenoic acid hydrochloride may be of clinical relevance for the prevention or treatment of th
medicine
-
thromboxane A2 may somehow mediate coughing induced by the angiotensin converting enzyme inhibitors. Patients on angiotensin converting enzyme inhibitors who develop cough may benefit from thromboxane A2 synthetase inhibitors
medicine
-
improvement of the renal function with the selective thromboxane A2 synthetase inhibitor (+/-)-6-(1-imidazolylmethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid hydrochloride hemihydrate
medicine
-
TXAS mRNA expression was found to be an independent prognostic marker for patients with bladder cancer
medicine
-
in addition to inhibitory activity, application of ONO-1301, i.e. ([5-[2-([[(1E)-phenyl(pyridin-3-yl)methylidene]amino]oxy)ethyl]-7,8-dihydronaphthalen-1-yl]oxy)acetic acid, significantly attenuates the development of pulmonary fibrosis and improves survival after treatment with bleomycin
medicine
-
thromboxane-A synthase protein is consistently upregulated in the cancer tissues from patients with colorectal carcinoma and also highly expressed in colonic cancer cell lines. Depletion of enzyme protein by antisense oligonucleotide inhibits proliferation of cancer cells
medicine
-
TBXAS1 gene polymorphisms are a marker for development of cerebral infarction, especially small-artery occlusion type in Korean population
medicine
-
the targeted inhibition of TXSA activity improves the efficiency of conventional alkylation chemotherapy in vivo
-
development of a screening assay for the in vitro evaluation of thromboxane A2 synthase inhibitors. Inhibitors of thromboxane synthase are regarded as potentially useful agents in the treatment of cardiovascular diseases and in the prevention of tumor cell metastases
pharmacology
-
the thromboxane A2 synthetase inhibitor 1-[3-(4-benzylhydryl-1-piperazinyl)propyl]-3-(1H-imidazol-1-ylmethyl)-1H-indole-6-carboxylic acid is a candidate anti-asthmatic drug