5.3.99.5: thromboxane-A synthase
This is an abbreviated version!
For detailed information about thromboxane-A synthase, go to the full flat file.
Word Map on EC 5.3.99.5
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5.3.99.5
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platelet
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prostaglandin
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arachidonic
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artery
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cyclooxygenase
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prostacyclin
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indomethacin
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endothelial
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endoperoxide
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pulmonary
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prostanoids
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aspirin
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dazoxiben
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coronary
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eicosanoids
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vasoconstrictor
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leukotriene
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imidazole
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hypertension
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thrombosis
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aorta
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hemodynamic
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antiplatelet
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6-keto-pgf1
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cox-2
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5-lipoxygenase
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6-keto-prostaglandin
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vasodilator
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antithrombotic
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ozagrel
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endothelium-dependent
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thrombus
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paf
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endothelium-derived
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bronchoconstriction
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6-keto
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platelet-rich
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constrictor
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collagen-induced
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aa-induced
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analysis
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medicine
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aspirin-treated
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pharmacology
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ticlopidine
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reocclusion
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meclofenamate
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f1alpha
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pgg2
-
iloprost
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antiaggregatory
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14c-arachidonic
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proaggregatory
- 5.3.99.5
- platelet
- prostaglandin
-
arachidonic
- artery
-
cyclooxygenase
- prostacyclin
- indomethacin
- endothelial
-
endoperoxide
- pulmonary
-
prostanoids
- aspirin
- dazoxiben
- coronary
-
eicosanoids
-
vasoconstrictor
-
leukotriene
- imidazole
- hypertension
- thrombosis
- aorta
-
hemodynamic
-
antiplatelet
-
6-keto-pgf1
- cox-2
-
5-lipoxygenase
-
6-keto-prostaglandin
-
vasodilator
-
antithrombotic
- ozagrel
-
endothelium-dependent
- thrombus
- paf
-
endothelium-derived
-
bronchoconstriction
-
6-keto
-
platelet-rich
-
constrictor
-
collagen-induced
-
aa-induced
- analysis
- medicine
-
aspirin-treated
- pharmacology
- ticlopidine
-
reocclusion
- meclofenamate
-
f1alpha
- pgg2
-
iloprost
-
antiaggregatory
-
14c-arachidonic
-
proaggregatory
Reaction
Synonyms
CYP5A1, Synthetase, thromboxane, TBXAS1, Thromboxan synthetase, thromboxane A synthase 1, thromboxane A-synthase, thromboxane A2 synthase, thromboxane A2 synthase 1, Thromboxane A2 synthetase, thromboxane synthase, Thromboxane synthetase, TXA synthase, TxA-synthase, TXA2 synthase, TXAS, TXS, TXSA, TxSI
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Activating Compound
Activating Compound on EC 5.3.99.5 - thromboxane-A synthase
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diosgenin
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10 microM increases cyclooxygenase-2 and thromboxane synthase expression and activities in HEL cells, 3.5fold at 96 h and 4.5fold at 144 h
additional information
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the catalytic activities of the binary phosphatidylethanolamine/phosphatidylcholine and phosphatidylserine/phosphatidylcholine and ternary phosphatidylcholine/phosphatidylethanolamine/phosphatidylserine are similar and increase relative to the unary phosphatidylcholine system
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