5.3.99.5: thromboxane-A synthase

This is an abbreviated version!
For detailed information about thromboxane-A synthase, go to the full flat file.

Word Map on EC 5.3.99.5

5.3.99.5

platelet

prostaglandin

arachidonic

artery

cyclooxygenase

prostacyclin

indomethacin

endothelial

endoperoxide

pulmonary

prostanoids

aspirin

dazoxiben

coronary

eicosanoids

vasoconstrictor

leukotriene

imidazole

hypertension

thrombosis

aorta

hemodynamic

antiplatelet

6-keto-pgf1

cox-2

5-lipoxygenase

6-keto-prostaglandin

vasodilator

antithrombotic

ozagrel

endothelium-dependent

thrombus

paf

endothelium-derived

bronchoconstriction

6-keto

platelet-rich

constrictor

collagen-induced

aa-induced

analysis

medicine

aspirin-treated

pharmacology

ticlopidine

reocclusion

meclofenamate

f1alpha

pgg2

iloprost

antiaggregatory

14c-arachidonic

proaggregatory

Reaction

(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate

(5Z,13E)-(15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dienoate

Synonyms

CYP5A1, Synthetase, thromboxane, TBXAS1, Thromboxan synthetase, thromboxane A synthase 1, thromboxane A-synthase, thromboxane A2 synthase, thromboxane A2 synthase 1, Thromboxane A2 synthetase, thromboxane synthase, Thromboxane synthetase, TXA synthase, TxA-synthase, TXA2 synthase, TXAS, TXS, TXSA, TxSI

ECTree

5 Isomerases

5.3 Intramolecular oxidoreductases

5.3.99 Other intramolecular oxidoreductases

5.3.99.5 thromboxane-A synthase

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Results	in table
5	Activating Compound
34	AA Sequence
13	Application
1	CAS Registry Number
9	Cloned(Commentary)
14	Cofactor
1714	Disease/ Diagnostics
11	Expression
6	General Information
1	General Stability
159	Inhibitors
3	Ki Value [mM]
14	KM Value [mM]
23	Localization
1	Metals/Ions
6	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
84	Organism
8	Pathway
2	pH Optimum
1	pH Range
1	pH Stability
31	Protein Variants
18	Purification (Commentary)
3	Reaction
2	Reaction Type
84	Reference
96	Source Tissue
9	Specific Activity [micromol/min/mg]
1	Storage Stability
101	Substrates and Products (Substrate)
6	Subunits
61	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

Sequence

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Sequence on EC 5.3.99.5 - thromboxane-A synthase

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Q96SQ9 pBLAST

CP2S1_HUMAN

Homo sapiens

504

55817

Swiss-Prot