5.3.99.5: thromboxane-A synthase
This is an abbreviated version!
For detailed information about thromboxane-A synthase, go to the full flat file.
Word Map on EC 5.3.99.5
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5.3.99.5
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platelet
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prostaglandin
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arachidonic
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artery
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cyclooxygenase
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prostacyclin
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indomethacin
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endothelial
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endoperoxide
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pulmonary
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prostanoids
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aspirin
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dazoxiben
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coronary
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eicosanoids
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vasoconstrictor
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leukotriene
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imidazole
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hypertension
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thrombosis
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aorta
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hemodynamic
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antiplatelet
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6-keto-pgf1
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cox-2
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5-lipoxygenase
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6-keto-prostaglandin
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vasodilator
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antithrombotic
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ozagrel
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endothelium-dependent
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thrombus
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paf
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endothelium-derived
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bronchoconstriction
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6-keto
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platelet-rich
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constrictor
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collagen-induced
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aa-induced
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analysis
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medicine
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aspirin-treated
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pharmacology
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ticlopidine
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reocclusion
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meclofenamate
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f1alpha
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pgg2
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iloprost
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antiaggregatory
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14c-arachidonic
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proaggregatory
- 5.3.99.5
- platelet
- prostaglandin
-
arachidonic
- artery
-
cyclooxygenase
- prostacyclin
- indomethacin
- endothelial
-
endoperoxide
- pulmonary
-
prostanoids
- aspirin
- dazoxiben
- coronary
-
eicosanoids
-
vasoconstrictor
-
leukotriene
- imidazole
- hypertension
- thrombosis
- aorta
-
hemodynamic
-
antiplatelet
-
6-keto-pgf1
- cox-2
-
5-lipoxygenase
-
6-keto-prostaglandin
-
vasodilator
-
antithrombotic
- ozagrel
-
endothelium-dependent
- thrombus
- paf
-
endothelium-derived
-
bronchoconstriction
-
6-keto
-
platelet-rich
-
constrictor
-
collagen-induced
-
aa-induced
- analysis
- medicine
-
aspirin-treated
- pharmacology
- ticlopidine
-
reocclusion
- meclofenamate
-
f1alpha
- pgg2
-
iloprost
-
antiaggregatory
-
14c-arachidonic
-
proaggregatory
Reaction
Synonyms
CYP5A1, Synthetase, thromboxane, TBXAS1, Thromboxan synthetase, thromboxane A synthase 1, thromboxane A-synthase, thromboxane A2 synthase, thromboxane A2 synthase 1, Thromboxane A2 synthetase, thromboxane synthase, Thromboxane synthetase, TXA synthase, TxA-synthase, TXA2 synthase, TXAS, TXS, TXSA, TxSI
ECTree
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Source Tissue
Source Tissue on EC 5.3.99.5 - thromboxane-A synthase
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thromboxane synthase, prostaglandin cyclase and cyclooxygenase COX-1 are widely distributed throughout normal aortic endothelium
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TXAS is expressed in the atherosclerotic lesion, associated with increased inflammatory cells, in particular M2 polarized macrophages
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TXAS is expressed in the atherosclerotic lesion, associated with increased inflammatory cells, in particular M2 polarized macrophages
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in normal lung tissue, TXS is moderately expressed in bronchial epithelial cells and weakly expressed in vascular smooth muscle cells
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adenocarcinomas and squamous cell carcinomas, enzyme expression profile, overview. Enzyme expression is higher in adenocarcinoma and female patients
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3164, 3167, 3168, 3169, 3170, 3171, 3174, 3175, 3177, 3178, 3179, 3180, 3182, 3186, 3189, 3190, 3192, 3194, 3198, 3200, 37485
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the higher staining intensities are in the ganglion cell and inner plexiform layers and in the outer plexiform layer, with more staining in the inner nuclear layer than in the outer nuclear layer
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the higher staining intensities are in the ganglion cell and inner plexiform layers and in the outer plexiform layer, with more staining in the inner nuclear layer than in the outer nuclear layer