4.2.1.9: dihydroxy-acid dehydratase

This is an abbreviated version!
For detailed information about dihydroxy-acid dehydratase, go to the full flat file.

Word Map on EC 4.2.1.9

4.2.1.9

branched-chain

dhads

fe-s

acetolactate

isomeroreductase

isobutanol

2-ketoisovalerate

reductoisomerase

2,3-butanediol

bcaas

ketol-acid

ilvbncd

drug development

analysis

synthesis

Reaction

Synonyms

2,3-dihydroxy acid hydrolyase, 2,3-dihydroxyisovalerate dehydratase, acetohydroxyacid dehydratase, AfIlv3A, AFUA_2G2410, alpha,beta-dihydroxy acid dehydratase, alpha,beta-dihydroxyisovalerate dehydratase, AT3G23940, DAD, dehydratase, dihydroxy acid, DHAD, dihydroxy acid dehydrase, dihydroxy acid dehydratase, dihydroxyacid dehydratase, H16_A2987, ilvC, IlvD, SsDHAD, VEG110, Vegetative protein 110

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.9 dihydroxy-acid dehydratase

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Results	in table
2	Activating Compound
49691	AA Sequence
5	Application
1	CAS Registry Number
10	Cloned(Commentary)
2	Cofactor
3	Expression
14	General Information
1	General Stability
6	IC50 Value
55	Inhibitors
1	Ki Value [mM]
27	KM Value [mM]
5	Localization
26	Metals/Ions
10	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
260	Organism
8	Oxidation Stability
14	Pathway
16	PDB ID
18	pH Optimum
4	pH Range
6	Protein Variants
10	Purification (Commentary)
3	Reaction
1	Reaction Type
60	Reference
10	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
141	Substrates and Products (Substrate)
6	Subunits
48	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
10	Temperature Stability [°C]
14	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 4.2.1.9 - dihydroxy-acid dehydratase

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0.024

Mycobacterium tuberculosis

purified native enzyme, pH 8.0, temperature not specified in the publication

0.132

0.18

0.416

1.63

Methanococcus aeolicus

33983

10.13

Neurospora crassa

33963

10.7

Saccharolobus solfataricus

Q97UB2

pH 7, 50°C, conversion of D-glycerate to pyruvate

732214

Aspergillus fumigatus

pH 8, 22°C

2.15

3.4

pH 7.0, 30°C

additional information

5 entries