4.2.1.9: dihydroxy-acid dehydratase

This is an abbreviated version!
For detailed information about dihydroxy-acid dehydratase, go to the full flat file.

Word Map on EC 4.2.1.9

4.2.1.9

branched-chain

dhads

fe-s

acetolactate

isomeroreductase

isobutanol

2-ketoisovalerate

reductoisomerase

2,3-butanediol

bcaas

ketol-acid

ilvbncd

drug development

analysis

synthesis

Reaction

Synonyms

2,3-dihydroxy acid hydrolyase, 2,3-dihydroxyisovalerate dehydratase, acetohydroxyacid dehydratase, AfIlv3A, AFUA_2G2410, alpha,beta-dihydroxy acid dehydratase, alpha,beta-dihydroxyisovalerate dehydratase, AT3G23940, DAD, dehydratase, dihydroxy acid, DHAD, dihydroxy acid dehydrase, dihydroxy acid dehydratase, dihydroxyacid dehydratase, H16_A2987, ilvC, IlvD, SsDHAD, VEG110, Vegetative protein 110

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.9 dihydroxy-acid dehydratase

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Results	in table
2	Activating Compound
49691	AA Sequence
5	Application
1	CAS Registry Number
10	Cloned(Commentary)
2	Cofactor
3	Expression
14	General Information
1	General Stability
6	IC50 Value
55	Inhibitors
1	Ki Value [mM]
27	KM Value [mM]
5	Localization
26	Metals/Ions
10	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
260	Organism
8	Oxidation Stability
14	Pathway
16	PDB ID
18	pH Optimum
4	pH Range
6	Protein Variants
10	Purification (Commentary)
3	Reaction
1	Reaction Type
60	Reference
10	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
141	Substrates and Products (Substrate)
6	Subunits
48	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
10	Temperature Stability [°C]
14	Turnover Number [1/s]

KM Value

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KM Value on EC 4.2.1.9 - dihydroxy-acid dehydratase

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0.33

(2R,3R)-2,3-dihydroxy-3-methylpentanoate

Spinacia oleracea

33985

0.71

(2R,3S)-2,3-dihydroxy-3-methylpentanoate

Spinacia oleracea

33985

0.97 - 2.1

2,3-Dihydroxy-3-methylbutanoate

2 entries

2.16 - 8.5

2,3-dihydroxy-3-methylpentanoate

5 entries

0.55

2,3-dihydroxybutanoate

Spinacia oleracea

33985

0.54 - 2.8

2,3-dihydroxyisovalerate

8 entries

1.78

3-cyclopropyl-2,3-dihydroxybutanoate

Spinacia oleracea

33985

1.75

D-erythronate

Spinacia oleracea

33981

2.42 - 7.8

D-gluconate

2 entries

3.7

DL-2,3-dihydroxyisovalerate

Mycobacterium tuberculosis

pH 8.0, temperature not specified in the publication

716148

0.65 - 10.1

L-threonate

2 entries