4.2.1.9: dihydroxy-acid dehydratase
This is an abbreviated version!
For detailed information about dihydroxy-acid dehydratase, go to the full flat file.
Word Map on EC 4.2.1.9
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4.2.1.9
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branched-chain
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dhads
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fe-s
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acetolactate
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isomeroreductase
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isobutanol
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2-ketoisovalerate
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reductoisomerase
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2,3-butanediol
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bcaas
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ketol-acid
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ilvbncd
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drug development
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analysis
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synthesis
- 4.2.1.9
-
branched-chain
-
dhads
- fe-s
- acetolactate
-
isomeroreductase
- isobutanol
- 2-ketoisovalerate
- reductoisomerase
- 2,3-butanediol
-
bcaas
-
ketol-acid
-
ilvbncd
- drug development
- analysis
- synthesis
Reaction
Synonyms
2,3-dihydroxy acid hydrolyase, 2,3-dihydroxyisovalerate dehydratase, acetohydroxyacid dehydratase, AfIlv3A, AFUA_2G2410, alpha,beta-dihydroxy acid dehydratase, alpha,beta-dihydroxyisovalerate dehydratase, AT3G23940, DAD, dehydratase, dihydroxy acid, DHAD, dihydroxy acid dehydrase, dihydroxy acid dehydratase, dihydroxyacid dehydratase, H16_A2987, ilvC, IlvD, SsDHAD, VEG110, Vegetative protein 110
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Application
Application on EC 4.2.1.9 - dihydroxy-acid dehydratase
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analysis
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the enzyme is used to quantify and investigate the biological oxidant stress activity of various redox-cycling chemicals. High sensitivity to inactivation by oxidants makes the enzyme useful for identification of compounds which increase oxyradical flux in the cell and for probing their mechanism of action
drug development
synthesis
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DHAD can be a potential drug/vaccine target, as it is absent in mammals
drug development
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DHAD can be a potential drug/vaccine target, as it is absent in mammals
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the enzyme can be used for a convenient one-step synthesis route from D-gluconate to 2-dehydro-3-deoxy-D-gluconate
synthesis
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the enzyme can be used for a convenient one-step synthesis route from D-gluconate to 2-dehydro-3-deoxy-D-gluconate
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