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4.2.1.9: dihydroxy-acid dehydratase

This is an abbreviated version!
For detailed information about dihydroxy-acid dehydratase, go to the full flat file.

Word Map on EC 4.2.1.9

Reaction

2,3-Dihydroxy-3-methylbutanoate
=
3-methyl-2-oxobutanoate
+
H2O

Synonyms

2,3-dihydroxy acid hydrolyase, 2,3-dihydroxyisovalerate dehydratase, acetohydroxyacid dehydratase, AfIlv3A, AFUA_2G2410, alpha,beta-dihydroxy acid dehydratase, alpha,beta-dihydroxyisovalerate dehydratase, AT3G23940, DAD, dehydratase, dihydroxy acid, DHAD, dihydroxy acid dehydrase, dihydroxy acid dehydratase, dihydroxyacid dehydratase, H16_A2987, ilvC, IlvD, SsDHAD, VEG110, Vegetative protein 110

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.9 dihydroxy-acid dehydratase

Application

Application on EC 4.2.1.9 - dihydroxy-acid dehydratase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
-
the enzyme is used to quantify and investigate the biological oxidant stress activity of various redox-cycling chemicals. High sensitivity to inactivation by oxidants makes the enzyme useful for identification of compounds which increase oxyradical flux in the cell and for probing their mechanism of action
drug development
synthesis