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4.2.1.84: nitrile hydratase

This is an abbreviated version!
For detailed information about nitrile hydratase, go to the full flat file.

Word Map on EC 4.2.1.84

Reaction

an aliphatic amide
=
A nitrile
+
H2O

Synonyms

3-cyanopyridine hydratase, acrylonitrile hydratase, aliphatic nitrile hydratase, ANHase, Co-type NHase, Co-type nitrile hydratase, cobalt-containing nitrile hydratase, CoIII-NHase, CtNHase, Fe-NHase, H-NHase, H-nitrilase, high-molecular mass nitrile hydratase, high-molecular weight nitrile hydratase, hydratase, nitrile, iron-type nitrile hydratase, L-Nhase, L-nitrilase, low-molecular mass nitrile hydratase, low-molecular weight nitrile hydratase, MbNHase, NHase, NHaseK, NI1 NHase, NilCo, NilFe, nitrilase, nitrile hydratase, NthAB, PaNit, ppNHase, ReNHase, TNHase, toyocamycin nitrile hydratase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.84 nitrile hydratase

Expression

Expression on EC 4.2.1.84 - nitrile hydratase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
analysis of optimal growth conditions: glycerol, mannitol, sorbitol, lactose, sucrose, citrate, acetate, succinate induce the enzyme production, as well as KH2PO4, K2HPO4 MgSO4, FeCl3, and CoCl2 addition to the medium at pH 7.0-9.0, 25°C, kinetics, overview
moderate induction of Rhodococcus erythropolis A4 nitrile hydratase gene expression by acetonitrile at the transcriptional level
no activity in presence of crotonamide in strain 03-03119
no activity in strain 02-10041 in absence of crotonamide
no activity in strain 03-03046 in presence of crotonamide