4.2.1.84: nitrile hydratase

This is an abbreviated version!
For detailed information about nitrile hydratase, go to the full flat file.

Reaction

Synonyms

3-cyanopyridine hydratase, acrylonitrile hydratase, aliphatic nitrile hydratase, ANHase, Co-type NHase, Co-type nitrile hydratase, cobalt-containing nitrile hydratase, CoIII-NHase, CtNHase, Fe-NHase, H-NHase, H-nitrilase, high-molecular mass nitrile hydratase, high-molecular weight nitrile hydratase, hydratase, nitrile, iron-type nitrile hydratase, L-Nhase, L-nitrilase, low-molecular mass nitrile hydratase, low-molecular weight nitrile hydratase, MbNHase, NHase, NHaseK, NI1 NHase, NilCo, NilFe, nitrilase, nitrile hydratase, NthAB, PaNit, ppNHase, ReNHase, TNHase, toyocamycin nitrile hydratase

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.84 nitrile hydratase

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Results	in table
24	Activating Compound
6842	AA Sequence
82	Application
1	CAS Registry Number
57	Cloned(Commentary)
8	Cofactor
25	Crystallization (Commentary)
33	Disease/ Diagnostics
15	Expression
19	General Information
14	General Stability
19	IC50 Value
218	Inhibitors
51	kcat/KM [mM/s]
39	Ki Value [mM]
181	KM Value [mM]
5	Localization
103	Metals/Ions
108	Molecular Weight [Da]
111	Natural Substrates/ Products (Substrates)
16	Organic Solvent Stability
815	Organism
1	Oxidation Stability
14	Pathway
159	PDB ID
71	pH Optimum
22	pH Range
12	pH Stability
3	pI Value
4	Posttranslational Modification
106	Protein Variants
58	Purification (Commentary)
27	Reaction
8	Reaction Type
340	Reference
9	Source Tissue
131	Specific Activity [micromol/min/mg]
10	Storage Stability
831	Substrates and Products (Substrate)
110	Subunits
195	Synonyms
1	Systematic Name
70	Temperature Optimum [°C]
14	Temperature Range [°C]
69	Temperature Stability [°C]
75	Turnover Number [1/s]

Synonyms

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Synonyms on EC 4.2.1.84 - nitrile hydratase

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

3-cyanopyridine hydratase

-

-

-

-

acrylonitrile hydratase

-

-

-

-

aliphatic nitrile hydratase

-

-

-

-

ANHase

2 entries

Co-type NHase

3 entries

Co-type nitrile hydratase

2 entries

cobalt-containing nitrile hydratase

3 entries

CoIII-NHase

4 entries

CtNHase

2 entries

Fe-NHase

Rhodococcus sp.

-

-

704017

H-NHase

4 entries

H-nitrilase

-

-

-

-

high-molecular mass nitrile hydratase

2 entries

high-molecular weight nitrile hydratase

2 entries

hydratase, nitrile

-

-

-

-

iron-type nitrile hydratase

2 entries

L-Nhase

6 entries

L-nitrilase

-

-

-

-

low-molecular mass nitrile hydratase

2 entries

low-molecular weight nitrile hydratase

2 entries

MbNHase

Monosiga brevicollis

A9V2C1

-

747192

NHase

58 entries

NHaseK

2 entries

NI1 NHase

-

-

-

-

NilCo

Comamonas testosteroni

-

-

675242

NilFe

Comamonas testosteroni

-

-

675242

nitrilase

2 entries

nitrile hydratase

20 entries

NthAB

Pseudomonas sp.

K9NKC3, K9NLN7

-

729043

PaNit

Pyrococcus abyssi

-

-

716057

ppNHase

2 entries

ReNHase

2 entries

TNHase

Streptomyces rimosus

B6CWJ3, B6CWJ4, B6CWJ5

-

729257

toyocamycin nitrile hydratase

Streptomyces rimosus

B6CWJ3, B6CWJ4, B6CWJ5

-

729257

ANHase

Rhodococcus sp.

-

acetonitrile hydratase

676087

ANHase

Rhodococcus sp. RHA1

-

acetonitrile hydratase

-

Co-type NHase

Pseudonocardia thermophila

Q7SID2

-

699611, 729123

Co-type NHase

Pseudonocardia thermophila

Q7SID3

-

729123

Co-type NHase

Pseudonocardia thermophila JCM 3095

Q7SID2, Q7SID3

-

-

Co-type nitrile hydratase

Pseudomonas putida

-

-

714254

Co-type nitrile hydratase

Pseudomonas putida NRRL-18668

-

-

-

cobalt-containing nitrile hydratase

Pseudonocardia thermophila

Q7SID2

-

648457, 729123

cobalt-containing nitrile hydratase

Pseudonocardia thermophila

Q7SID3

-

648457, 729123

cobalt-containing nitrile hydratase

Pseudonocardia thermophila JCM 3095

Q7SID2, Q7SID3

-

-

CoIII-NHase

Pseudonocardia thermophila

-

-

697734

CoIII-NHase

Pseudonocardia thermophila JCM 3095

-

-

-

CoIII-NHase

Rhodococcus erythropolis

-

-

697734

CoIII-NHase

Rhodococcus erythropolis N-771

-

-

-

CtNHase

Comamonas testosteroni

J9PBS0; J9PBS1

-

748242

CtNHase

Comamonas testosteroni Ni1

J9PBS0; J9PBS1

-

-

H-NHase

-

-

-

-

H-NHase

Rhodococcus rhodochrous

-

-

714229

H-NHase

Rhodococcus rhodochrous

P21219; P21220

-

749108

H-NHase

Rhodococcus rhodochrous J1

P21219; P21220

-

-

high-molecular mass nitrile hydratase

Rhodococcus rhodochrous

-

-

714229

high-molecular mass nitrile hydratase

Rhodococcus rhodochrous J1

-

-

-

high-molecular weight nitrile hydratase

Rhodococcus rhodochrous

P21219; P21220

-

749108

high-molecular weight nitrile hydratase

Rhodococcus rhodochrous J1

P21219; P21220

-

-

iron-type nitrile hydratase

Rhodococcus equi

-

-

730013

iron-type nitrile hydratase

Rhodococcus equi TG328-2

-

-

-

L-Nhase

-

-

-

-

L-Nhase

Rhodococcus fascians

-

-

704478

L-Nhase

Rhodococcus fascians DSM 43985

-

-

-

L-Nhase

Rhodococcus rhodochrous

-

-

714229

L-Nhase

Rhodococcus rhodochrous

P29378; P29379

-

749108

L-Nhase

Rhodococcus rhodochrous J1

P29378; P29379

-

-

low-molecular mass nitrile hydratase

Rhodococcus rhodochrous

-

-

714229

low-molecular mass nitrile hydratase

Rhodococcus rhodochrous J1

-

-

-

low-molecular weight nitrile hydratase

Rhodococcus rhodochrous

P29378; P29379

-

749108

low-molecular weight nitrile hydratase

Rhodococcus rhodochrous J1

P29378; P29379

-

-

NHase

-

-

-

-

NHase

Aeribacillus pallidus

-

-

705203

NHase

Aeribacillus pallidus RAPc8

-

-

-

NHase

Alcaligenes faecalis

-

-

715804

NHase

Alcaligenes faecalis CCTCC M 208168

-

-

-

NHase

Aplysina cavernicola

-

-

730311

NHase

Bacillus sp. (in: Bacteria)

-

-

699612

NHase

Bacillus sp. (in: Bacteria)

Q7SID2, Q7SID3

-

730090

NHase

Bacillus sp. (in: Bacteria) SC-105-1

Q7SID2, Q7SID3

-

-

NHase

Bacillus subtilis

-

-

715804

NHase

Bacillus subtilis CCTCC M 206038

-

-

-

NHase

Comamonas testosteroni

-

-

675242

NHase

Comamonas testosteroni

Q5XPL4, Q5XPL5

-

729148

NHase

Comamonas testosteroni 5-MGAM-4D

Q5XPL4, Q5XPL5

-

-

NHase

Mesorhizobium sp.

-

-

701026

NHase

Mesorhizobium sp. BNC1

-

-

-

NHase

Monosiga brevicollis

A9V2C1

-

700890

NHase

Nitriliruptor alkaliphilus

-

-

701585

NHase

Nocardia sp.

Q8GJG6

-

675472

NHase

Nocardia sp. YS-2002

Q8GJG6

-

-

NHase

Pseudomonas putida

-

-

729148, 730077

NHase

Pseudomonas putida

A5W402

-

730224

NHase

Pseudomonas putida NRRL-18668

-

-

-

NHase

Pseudonocardia thermophila

-

-

675502, 697296, 697305, 730090

NHase

Pseudonocardia thermophila

Q7SID2

-

648457, 699611, 699612, 728998, 729123, 729148, 729896

NHase

Pseudonocardia thermophila

Q7SID3

-

648457, 729123, 729148, 729896

NHase

Pseudonocardia thermophila JCM 3095

Q7SID2, Q7SID3

-

-

NHase

Rhodococcus boritolerans

-

-

715804

NHase

Rhodococcus boritolerans CCTCC M 208108

-

-

-

NHase

Rhodococcus equi

-

-

701856, 730013

NHase

Rhodococcus equi TG328-2

-

-

-

NHase

Rhodococcus erythropolis

-

-

671808, 672758, 695669, 699597, 704716, 729825, 730543

NHase

Rhodococcus erythropolis

P13448

-

728998

NHase

Rhodococcus erythropolis AJ270

P13448

-

-

NHase

Rhodococcus erythropolis MTCC 1526

-

-

-

NHase

Rhodococcus erythropolis N4

-

-

-

NHase

Rhodococcus erythropolis N771

-

-

-

NHase

Rhodococcus qingshengii

-

-

714580

NHase

Rhodococcus qingshengii ZA0707

-

-

-

NHase

Rhodococcus rhodochrous

-

-

703995

NHase

Rhodococcus rhodochrous PA-34

-

-

-

NHase

Rhodococcus ruber

-

-

701594, 715804, 730090

NHase

Rhodococcus ruber CCTCC M 206040

-

-

-

NHase

Rhodococcus ruber CGMCC3090

-

-

-

NHase

Rhodococcus ruber TH

-

-

-

NHase

Rhodococcus sp.

-

-

672689, 672727, 673098, 676087, 696768, 699044, 703230, 715804

NHase

Rhodococcus sp. AJ270

-

-

-

NHase

Rhodococcus sp. N595

-

-

-

NHase

Rhodococcus sp. N771

-

-

-

NHase

Rhodococcus sp. RHA1

-

-

-

NHase

Rhodococcus sp. SHZ-1

-

-

-

NHase

Rhodopseudomonas palustris

-

-

706803, 730543

NHase

Rhodopseudomonas palustris CGA009

-

-

-

NHase

Rhodopseudomonas palustris HaA2

-

-

-

NHase

Serratia marcescens

-

-

706917, 715804

NHase

Serratia marcescens CCTCC M 208231

-

-

-

NHase

Serratia marcescens ZJB-09104

-

-

-

NHase

Streptomyces rimosus

B6CWJ3, B6CWJ4, B6CWJ5

-

729257

NHaseK

Klebsiella oxytoca

A0A0H3HE78; A0A0H3H964

-

747361

NHaseK

Klebsiella oxytoca DSM 4798

A0A0H3HE78; A0A0H3H964

-

-

nitrilase

-

-

-

-

nitrilase

Pyrococcus abyssi

-

-

716057

nitrile hydratase

Comamonas oleophilus

-

-

673399

nitrile hydratase

Comamonas testosteroni

-

-

675242

nitrile hydratase

no activity in Arabidopsis thaliana

-

-

674012

nitrile hydratase

Nocardia sp.

-

-

677265

nitrile hydratase

Nocardia sp.

Q8GJG6

-

675472

nitrile hydratase

Nocardia sp. 108

-

-

-

nitrile hydratase

Nocardia sp. YS-2002

Q8GJG6

-

-

nitrile hydratase

Nocardia transvalensis

-

-

673399

nitrile hydratase

Pseudonocardia thermophila

-

-

675502

nitrile hydratase

Pseudonocardia thermophila JCM 3095

-

-

-

nitrile hydratase

Rhodococcus erythropolis

-

-

671808, 672758, 673399

nitrile hydratase

Rhodococcus erythropolis AJ270

-

-

-

nitrile hydratase

Rhodococcus rhodochrous

-

-

673399

nitrile hydratase

Rhodococcus sp.

-

-

672689, 672727, 673098, 676087

nitrile hydratase

Rhodococcus sp. AJ270

-

-

-

nitrile hydratase

Rhodococcus sp. N771

-

-

-

nitrile hydratase

Rhodococcus sp. RHA1

-

-

-

nitrile hydratase

Rhodococcus sp. SHZ-1

-

-

-

nitrile hydratase

Sinapis alba

-

-

674012

nitrile hydratase

Sinapis arvensis

-

-

674012

ppNHase

Pseudomonas putida

-

-

714254

ppNHase

Pseudomonas putida NRRL-18668

-

-

-

ReNHase

Rhodococcus equi

-

-

730013

ReNHase

Rhodococcus equi TG328-2

-

-

-