3.7.1.3: kynureninase
This is an abbreviated version!
For detailed information about kynureninase, go to the full flat file.
Word Map on EC 3.7.1.3
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3.7.1.3
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3-hydroxyanthranilic
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medicine
-
quinolinic
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3-hydroxykynurenine
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kynurenic
-
anthranilic
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indoleamine
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3-monooxygenase
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l-tryptophan
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ido
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3,4-dioxygenase
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xanthurenic
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aminocarboxymuconate-semialdehyde
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3-hydroxylase
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quin
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excitotoxins
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quinonoid
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pyrrolase
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marginalis
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indoleamine-2,3-dioxygenase
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synthesis
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b6-deficient
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drug development
- 3.7.1.3
-
3-hydroxyanthranilic
- medicine
-
quinolinic
- 3-hydroxykynurenine
-
kynurenic
-
anthranilic
- indoleamine
-
3-monooxygenase
- l-tryptophan
-
ido
-
3,4-dioxygenase
-
xanthurenic
- aminocarboxymuconate-semialdehyde
-
3-hydroxylase
-
quin
-
excitotoxins
-
quinonoid
-
pyrrolase
- marginalis
- indoleamine-2,3-dioxygenase
- synthesis
-
b6-deficient
- drug development
Reaction
Synonyms
HsKynase, Kynase, KYNU, kynureninase, L-kynurenine hydrolase, PfKynase
ECTree
3.7.1.3 kynureninaseAdvanced search results
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results (Turnover Number
Turnover Number on EC 3.7.1.3 - kynureninase
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TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.08
2-amino-4-(2-chlorophenyl)-4-oxobutanoic acid
-
at 37°C in 0.04 M potassium phosphate, pH 7.8
0.05
2-amino-4-(2-methoxyphenyl)-4-oxobutanoic acid
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at 37°C in 0.04 M potassium phosphate, pH 7.8
0.38
2-amino-4-(4-methoxyphenyl)-4-oxobutanoic acid
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at 37°C in 0.04 M potassium phosphate, pH 7.8
0.06
2-fluorobenzoyl-DL-alanine
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at 37°C in 0.04 M potassium phosphate, pH 7.8
1.83
beta-(4-chlorobenzoyl)-DL-alanine
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at 37°C in 0.04 M potassium phosphate, pH 7.8
0.91
beta-(4-methylbenzoyl)-DL-alanine
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at 37°C in 0.04 M potassium phosphate, pH 7.8
0.001
beta-(4-trifluoromethylbenzoyl)-DL-alanine
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at 37°C in 0.04 M potassium phosphate, pH 7.8
0.23
3,5-dibromo-L-kynurenine
pH 8.0, 37°C, recombinant enzyme
0.0039
3-hydroxy-L-kynurenine
kcat less than 0.0039 1/s, mutant enzyme N333T, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
0.0109
3-hydroxy-L-kynurenine
kcat less than 0.0109 1/s, mutant enzyme S332G/N333T, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
3.5
3-hydroxy-L-kynurenine
wild type enzyme, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
6.3
5-bromo-3-chloro-DL-kynurenine
pH 8.0, 37°C, recombinant enzyme
0.007
L-kynurenine
mutant enzyme H102W/N333T, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
0.017
L-kynurenine
mutant enzyme S332G/N333T, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
0.018
L-kynurenine
Km above 0.51 mM, mutant enzyme H102W/S332G/N333T, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
0.026
L-kynurenine
mutant enzyme N333T, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
0.23
L-kynurenine
wild type enzyme, in 30 mM potassium phosphate, pH 8.0, and 0.04 mM pyridoxal 5'-phosphate, at 37°C
