3.7.1.3: kynureninase
This is an abbreviated version!
For detailed information about kynureninase, go to the full flat file.
Word Map on EC 3.7.1.3
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3.7.1.3
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3-hydroxyanthranilic
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medicine
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quinolinic
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3-hydroxykynurenine
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kynurenic
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anthranilic
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indoleamine
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3-monooxygenase
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l-tryptophan
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ido
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3,4-dioxygenase
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xanthurenic
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aminocarboxymuconate-semialdehyde
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3-hydroxylase
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quin
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excitotoxins
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quinonoid
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pyrrolase
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marginalis
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indoleamine-2,3-dioxygenase
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synthesis
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b6-deficient
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drug development
- 3.7.1.3
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3-hydroxyanthranilic
- medicine
-
quinolinic
- 3-hydroxykynurenine
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kynurenic
-
anthranilic
- indoleamine
-
3-monooxygenase
- l-tryptophan
-
ido
-
3,4-dioxygenase
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xanthurenic
- aminocarboxymuconate-semialdehyde
-
3-hydroxylase
-
quin
-
excitotoxins
-
quinonoid
-
pyrrolase
- marginalis
- indoleamine-2,3-dioxygenase
- synthesis
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b6-deficient
- drug development
Reaction
Synonyms
HsKynase, Kynase, KYNU, kynureninase, L-kynurenine hydrolase, PfKynase
ECTree
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Application on EC 3.7.1.3 - kynureninase
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drug development
medicine
synthesis
additional information
the enzym eis a target for the design of potent and/or selective inhibitors of bacterial kynureninase
drug development
the enzyme is a target for the design of potent and/or selective inhibitors of human kynureninase
medicine
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tryptophan metabolism
medicine
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progressive decline in the enzyme activity involved in tryptophan metabolism along the kynurenine pathway in rat tissue with age
medicine
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xanthurenic aciduria is linked to a mutation in the gene encoding kynureninase
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of inhibitors of kynureninase could prove to be useful in the development of the successful treatment regimen for neurological disorders such as septicemia, AIDS related dementia, Lyme disease, Huntington's and Alzheimer's disease
synthesis
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of inhibitors of kynureninase could prove to be useful in the development of the successful treatment regimen for neurological disorders such as septicemia, AIDS related dementia, Lyme disease, Huntington's and Alzheimer's disease
synthesis
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of inhibitors of kynureninase could prove to be useful in the development of the successful treatment regimen for neurological disorders such as septicemia, AIDS related dementia, Lyme disease, Huntington's and Alzheimer's disease
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cosmid pRA3 contains a trp operon that resembles that of the pathogen Chlamydophila caviae, containing the unusual kynU gene, which specifies kynureinase
additional information
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cosmid pRA3 contains a trp operon that resembles that of the pathogen Chlamydophila caviae, containing the unusual kynU gene, which specifies kynureinase