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3.6.1.59: 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

This is an abbreviated version!
For detailed information about 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.59

Reaction

a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA]
+
H2O
=
N7-methylguanosine 5'-phosphate
+
a 5'-diphospho-[mRNA]

Synonyms

Dcps, Dcs1, EC 3.6.1.30, m7GpppN m7GMP phosphohydrolase, m7GpppX pyrophosphatase, scavenger mRNA decapping enzyme, yDcps, YLR270W

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

Purification

Purification on EC 3.6.1.59 - 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
bisphosphonate mRNA cap analog attached to Sepharose for affinity chromatography of decapping enzymes
-
HisTrap, SP, and Q resin column chromatography
-