3.6.1.59: 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

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For detailed information about 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase, go to the full flat file.

Reaction

Synonyms

Dcps, Dcs1, EC 3.6.1.30, m7GpppN m7GMP phosphohydrolase, m7GpppX pyrophosphatase, scavenger mRNA decapping enzyme, yDcps, YLR270W

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

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Results	in table
1086	AA Sequence
1	Application
4	Cloned(Commentary)
3	Crystallization (Commentary)
2	Disease/ Diagnostics
5	General Information
2	IC50 Value
6	Inhibitors
2	kcat/KM [mM/s]
3	KM Value [mM]
4	Localization
1	Metals/Ions
2	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
15	Organism
22	PDB ID
3	pH Optimum
1	pI Value
7	Purification (Commentary)
2	Reaction
15	Reference
2	Source Tissue
58	Substrates and Products (Substrate)
5	Subunits
20	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Turnover Number [1/s]

Disease

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Disease on EC 3.6.1.59 - 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Intellectual Disability

Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects.

25712129

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