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Kim, Y.P.; Kahng, J.B.; Choi, J.Y.
Adenosine diphosphate ribose pyrophosphohydrolase in human skin
J. Dermatol.
7
11-15
1980
Homo sapiens
brenda
Wu, J.M.; Lennon, M.B.; Suhadolnik, R.J.
Catabolism of NAD+ in rabbit reticulocyte lysates
Biochim. Biophys. Acta
520
588-597
1978
Oryctolagus cuniculus
brenda
Doherty, M.D.; Morrison, J.F.
The hydrolysis of adenosine diphosphate ribose by a specific phosphohydrolase of rabbit-muscle extracts
Biochim. Biophys. Acta
65
364-366
1962
Oryctolagus cuniculus
brenda
Bernet, D.; Pinto, R.M.; Costas, M.J.; Canales, J.; Cameselle, J.C.
Rat liver mitochondrial ADP-ribose pyrophosphatase in the matrix space with low Km for free ADP-ribose
Biochem. J.
299
679-682
1994
Rattus norvegicus
brenda
Sheikh, S.; O'Handley, S.F.; Dunn, C.A.; Bessman, M.J.
Identification and characterization of the nudix hydrolase from the archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase
J. Biol. Chem.
273
20924-20928
1998
Methanocaldococcus jannaschii
brenda
Kim, J.S.; Kim, W.Y.; Rho, H.W.; Park, J.W.; Park, B.H.; Han, M.K.; Kim, U.H.; Kim, H.R.
Purification and characterization of adenosine diphosphate ribose pyrophosphatase from human erythrocytes
Int. J. Biochem. Cell Biol.
30
629-638
1998
Homo sapiens
brenda
Dunn, C.A.; OæHandley, S.F.; Frick, D.N.; Bessman, M.J.
Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance
J. Biol. Chem.
274
32318-32324
1999
Saccharomyces cerevisiae, Escherichia coli, Methanocaldococcus jannaschii, Cereibacter sphaeroides, Haemophilus influenzae (P44684), Bacillus subtilis (P54570), Bacillus subtilis
brenda
Ribeiro, J.M.; Cameselle, J.C.; Fernandez, A.; Canales, J.; Pinto, R.M.; Costas, M.J.
Inhibition of ADP-ribose pyrophosphatase-I by nitric-oxide-generating systems: a mechanism linking nitric oxide to processes dependent on free ADP-ribose
Biochem. Biophys. Res. Commun.
213
1075-1081
1995
Rattus norvegicus
brenda
Fernandez, A.; Ribeiro, J.M.; Costas, M.J.; Pinto, R.M.; Canales, J.; Cameselle, J.C.
Specific ADP-ribose pyrophosphatase from Artemia cysts and rat liver: effects of nitroprusside, fluoride and ionic strength
Biochim. Biophys. Acta
1290
121-127
1996
Artemia sp., Rattus norvegicus
brenda
Canales, J.; Pinto, R.M.; Costas, M.J.; Hernandez, M.T.; Miro, A.; Bernet, D.; Fernandez, A.; Cameselle, J.C.
Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatase different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg2+- and/or Mn2+-depeneent hydrolases acting on ADP-ribose
Biochim. Biophys. Acta
1246
167-177
1995
Rattus norvegicus
brenda
Ribeiro, J.M.; Agudo, A.; Costas, M.J.; Cameselle, J.C.
Rat liver ADP-ribose pyrophosphatase-I as an in vitro target of the acetaminophen metabolite N-acetyl-p-benzoquinoneimine
Biochim. Biophys. Acta
1336
403-4o8
1997
Rattus norvegicus
brenda
Ribeiro, J.M.; Costas, M.J.; Cameselle, J.C.
ADP-ribose pyrophosphatase-I partially purified from livers of rats overdosed with acetaminophen reveals enzyme inhibition in vivo reverted in vitro by dithiothreitol
J. Biochem. Mol. Toxicol.
13
171-177
1999
Rattus norvegicus
brenda
Gasmi, L.; Cartwright, J.L.; McLennan, A.G.
Cloning, expression and characterization of YSA1H, a human adenosine 5'-diphosphosugar pyrophosphatase possessing a MutT motif
Biochem. J.
344
331-337
1999
Homo sapiens (Q9UKK9), Homo sapiens
brenda
Yoshiba, S.; Nakagawa, N.; Masui, R.; Shibata, T.; Inoue, Y.; Yokoyama, S.; Kuramitsu, S.
Overproduction, crystallization and preliminary diffraction data of ADP-ribose pyrophosphatase from Thermus thermophilus HB8
Acta Crystallogr. Sect. D
59
1840-1842
2003
Thermus thermophilus (Q84CU3), Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q84CU3)
brenda
Gabelli, S.B.; Bianchet, M.A.; Ohnishi, Y.; Ichikawa, Y.; Bessman, M.J.; Amzel, L.M.
Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase
Biochemistry
41
9279-9285
2002
Escherichia coli (Q93K97), Escherichia coli
brenda
Ribeiro, J.M.; Carloto, A.; Costas, M.J.; Cameselle, J.C.
Human placenta hydrolases active on free ADP-ribose: an ADP-sugar pyrophosphatase and a specific ADP-ribose pyrophosphatase
Biochim. Biophys. Acta
1526
86-94
2001
Homo sapiens
brenda
Lin, S.; Gasmi, L.; Xie, Y.; Ying, K.; Gu, S.; Wang, Z.; Jin, H.; Chao, Y.; Wu, C.; Zhou, Z.; Tang, R.; Mao, Y.; McLennan, A.G.
Cloning, expression and characterisation of a human Nudix hydrolase specific for adenosine 5'-diphosphoribose (ADP-ribose)
Biochim. Biophys. Acta
1594
127-135
2001
Homo sapiens (Q9BW91), Homo sapiens
brenda
Okuda, K.; Nishiyama, Y.; Morita, E.H.; Hayashi, H.
Identification and characterization of NuhA, a novel Nudix hydrolase specific for ADP-ribose in the cyanobacterium Synechococcus sp. PCC 7002
Biochim. Biophys. Acta
1699
245-252
2004
Synechococcus sp. (Q83ZD0), Synechococcus sp.
brenda
Yang, H.; Slupska, M.M.; Wei, Y.F.; Tai, J.H.; Luther, W.M.; Xia, Y.R.; Shih, D.M.; Chiang, J.H.; Baikkalov, C.; Fitz-Gibbon, S.; Phan, I.T.; Conrad, A.; Miller, J.H.
Cloning and characterization of a new member of nudix hydrolases from human and mouse
J. Biol. Chem.
275
8844-8853
2000
Mus musculus, Homo sapiens (Q9UKK9), Homo sapiens
brenda
Perraud, A.L.; Shen, B.; Dunn, C.A.; Rippe, K.; Smith, M.K.; Bessman, M.J.; Stoddard, B.L.; Scharenberg, A.M.
NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase
J. Biol. Chem.
278
1794-1801
2003
Homo sapiens
brenda
Yoshiba, S.; Ooga, T.; Nakagawa, N.; Shibata, T.; Inoue, Y.; Yokoyama, S.; Kuramitsu, S.; Masui, R.
Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal
J. Biol. Chem.
279
37163-37174
2004
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
brenda
Gabelli, S.B.; Bianchet, M.A.; Bessman, M.J.; Amzel, L.M.
The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family
Nat. Struct. Biol.
8
467-472
2001
Escherichia coli (Q93K97), Escherichia coli
brenda
Ooga, T.; Yoshiba, S.; Nakagawa, N.; Kuramitsu, S.; Masui, R.
Molecular mechanism of the Thermus thermophilus ADP-ribose pyrophosphatase from mutational and kinetic studies
Biochemistry
44
9320-9329
2005
Thermus thermophilus
brenda
Carloto, A.; Costas, M.J.; Cameselle, J.C.; McLennan, A.G.; Ribeiro, J.M.
The specific, submicromolar-K(m) ADP-ribose pyrophosphatase purified from human placenta is enzymically indistinguishable from recombinant NUDT9 protein, including a selectivity for Mn(2+) as activating cation and increase in K(m) for ADP-ribose, both eli
Biochim. Biophys. Acta
1760
1545-1551
2006
Homo sapiens
brenda
Okuda, K.; Hayashi, H.; Nishiyama, Y.
Systematic characterization of the ADP-ribose pyrophosphatase family in the Cyanobacterium Synechocystis sp. strain PCC 6803
J. Bacteriol.
187
4984-4991
2005
Synechocystis sp.
brenda
Ogawa, T.; Ueda, Y.; Yoshimura, K.; Shigeoka, S.
Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana
J. Biol. Chem.
280
25277-25283
2005
Arabidopsis thaliana
brenda
Jambunathan, N.; Mahalingam, R.
Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling
Planta
224
1-11
2006
Arabidopsis sp.
brenda
Yu, H.N.; Song, E.K.; Yoo, S.M.; Lee, Y.R.; Han, M.K.; Yim, C.Y.; Kwak, J.Y.; Kim, J.S.
Activation of NUDT5, an ADP-ribose pyrophosphatase, by nitric oxide-mediated ADP-ribosylation
Biochem. Biophys. Res. Commun.
354
764-768
2007
Homo sapiens
brenda
Wakamatsu, T.; Nakagawa, N.; Kuramitsu, S.; Masui, R.
Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8
J. Bacteriol.
190
1108-1117
2008
Thermus thermophilus (Q84CU3), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q84CU3)
brenda
Zha, M.; Guo, Q.; Zhang, Y.; Yu, B.; Ou, Y.; Zhong, C.; Ding, J.
Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies
J. Mol. Biol.
379
568-578
2008
Homo sapiens, Homo sapiens (Q9UKK9)
brenda
Huang, N.; Sorci, L.; Zhang, X.; Brautigam, C.A.; Li, X.; Raffaelli, N.; Magni, G.; Grishin, N.V.; Osterman, A.L.; Zhang, H.
Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism
Structure
16
196-209
2008
Synechocystis sp. (Q55928), Synechocystis sp., Francisella tularensis (Q5NHR1), Francisella tularensis
brenda
Ge, J.; Wei, Z.; Huang, Y.; Yin, J.; Zhou, Z.; Zhong, J.
AcMNPV ORF38 protein has the activity of ADP-ribose pyrophosphatase and is important for virus replication
Virology
361
204-211
2007
Autographa californica multiple nucleopolyhedrovirus
brenda
Ogawa, T.; Ishikawa, K.; Harada, K.; Fukusaki, E.; Yoshimura, K.; Shigeoka, S.
Overexpression of an ADP-ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants
Plant J.
57
289-301
2009
Arabidopsis thaliana (Q94B74)
brenda
Goncalves, A.M.; Fioravanti, E.; Stelter, M.; McSweeney, S.
Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans
Acta Crystallogr. Sect. F
65
1083-1087
2009
Deinococcus radiodurans (Q9RSC1), Deinococcus radiodurans
brenda
Ito, R.; Sekiguchi, M.; Setoyama, D.; Nakatsu, Y.; Yamagata, Y.; Hayakawa, H.
Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein
J. Biochem.
149
731-738
2011
Homo sapiens (Q9UKK9), Homo sapiens
brenda
Zha, M.; Zhong, C.; Peng, Y.; Hu, H.; Ding, J.
Crystal structures of human NUDT5 reveal insights into the structural basis of the substrate specificity
J. Mol. Biol.
364
1021-1033
2006
Homo sapiens (Q9UKK9), Homo sapiens
brenda
Okazaki, N.; Adachi, M.; Tamada, T.; Kurihara, K.; Ooga, T.; Kamiya, N.; Kuramitsu, S.; Kuroki, R.
Crystallization and preliminary neutron diffraction studies of ADP-ribose pyrophosphatase-I from Thermus thermophilus HB8
Acta Crystallogr. Sect. F
68
49-52
2012
Thermus thermophilus (Q84CU3), Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q84CU3)
brenda
Ishikawa, K.; Yoshimura, K.; Ogawa, T.; Shigeoka, S.
Distinct regulation of Arabidopsis ADP-ribose/NADH pyrophosphohydrolases, AtNUDX6 and 7, in biotic and abiotic stress responses
Plant Signal. Behav.
5
839-841
2010
Arabidopsis thaliana (Q9SU14)
brenda
Karuppiah, V.; Thistlethwaite, A.; Dajani, R.; Warwicker, J.; Derrick, J.P.
Structure and mechanism of the bifunctional CinA enzyme from Thermus thermophilus
J. Biol. Chem.
289
33187-33197
2014
Thermus thermophilus (Q5SHB0), Thermus thermophilus, Thermus thermophilus DSM 579 (Q5SHB0)
brenda
Cabezas, A.; Ribeiro, J.; Rodrigues, J.; Lopez-Villamizar, I.; Fernandez, A.; Canales, J.; Pinto, R.; Costas, M.; Cameselle, J.
Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent adpribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase
PLoS ONE
10
e0118680
2015
Homo sapiens (W0NWJ0), Homo sapiens
brenda
Rodrigues, J.; Fernandez, A.; Canales, J.; Cabezas, A.; Ribeiro, J.; Costas, M.; Cameselle, J.
Characterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family
PLoS ONE
7
e42249
2012
Danio rerio (Q7T291), Danio rerio
brenda
Rafty, L.A.; Schmidt, M.T.; Perraud, A.L.; Scharenberg, A.M.; Denu, J.M.
Analysis of O-acetyl-ADP-ribose as a target for Nudix ADP-ribose hydrolases
J. Biol. Chem.
277
47114-47122
2002
Mus musculus
brenda
Arimori, T.; Tamaoki, H.; Nakamura, T.; Kamiya, H.; Ikemizu, S.; Takagi, Y.; Ishibashi, T.; Harashima, H.; Sekiguchi, M.; Yamagata, Y.
Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res.
39
8972-8983
2011
Homo sapiens (Q9UKK9), Homo sapiens
brenda
Furuike, Y.; Akita, Y.; Miyahara, I.; Kamiya, N.
ADP-ribose pyrophosphatase reaction in crystalline state conducted by consecutive binding of two manganese (II) ions as cofactors
Biochemistry
55
1801-1812
2016
Thermus thermophilus, Thermus thermophilus (Q84CU3), Mycobacterium tuberculosis (O33199), Escherichia coli (Q93K97), Homo sapiens (Q9UKK9), Mycobacterium tuberculosis CDC 1551 (O33199), Mycobacterium tuberculosis Oshkosh (O33199)
brenda
Njuguna, E.; Coussens, E.G.; Neyt, P.; Aesaert, S.; Storme, V.; Demuynck, K.; Vanhaeren, H.; Dhondt, S.; van Haver, Y.; Paul, L.; Inze, D.; Nelissen, H.; van Lijsebettens, M.
Functional analysis of Arabidopsis and maize transgenic lines overexpressing the ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7
Int. J. Dev. Biol.
63
45-55
2019
Arabidopsis thaliana (Q9SU14), Arabidopsis thaliana, Arabidopsis thaliana Col-0 (Q9SU14)
brenda
Ribeiro, J.M.; Canales, J.; Cabezas, A.; Rodrigues, J.R.; Pinto, R.M.; Lopez-Villamizar, I.; Costas, M.J.; Cameselle, J.C.
Specific cyclic ADP-ribose phosphohydrolase obtained by mutagenic engineering of Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
Sci. Rep.
8
1036
2018
Homo sapiens (Q3LIE5)
brenda