Literature summary for 3.6.1.13 extracted from

Fernandez, A.; Ribeiro, J.M.; Costas, M.J.; Pinto, R.M.; Canales, J.; Cameselle, J.C.
Specific ADP-ribose pyrophosphatase from Artemia cysts and rat liver: effects of nitroprusside, fluoride and ionic strength (1996), Biochim. Biophys. Acta, 1290, 121-127.

Search for more literature for 3.6.1.13

Inhibitors

Inhibitors	Comment	Organism	Structure
F-	0.010 mM NaF or KF, 50% inhibition. 0.2 mM NaF or KF, complete inhibition	Artemia sp.
F-	-	Rattus norvegicus
nitroprusside	nitroprusside in presence of dithiothreitol diminishes Vmax and increases Km	Artemia sp.
nitroprusside	-	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0068	-	ADPribose	-	Artemia sp.

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	-	Rattus norvegicus
Mg2+	divalent cation required, Mg2+ or Mn2+. Mg2+ is much more effective than Mn2+	Artemia sp.
Mn2+	-	Rattus norvegicus
Mn2+	divalent cation required, Mg2+ or Mn2+. Mg2+ is much more effective than Mn2+	Artemia sp.

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
31000	-	gel filtration	Artemia sp.

Organism

Organism	UniProt	Comment	Textmining
Artemia sp.	-	-	-
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
partial	Artemia sp.

Source Tissue

Source Tissue	Comment	Organism	Textmining
cyst	-	Artemia sp.	-
liver	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.2	-	-	Artemia sp.

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ADPribose + H2O	-	Rattus norvegicus	AMP + D-ribose 5-phosphate	-	?
ADPribose + H2O	-	Artemia sp.	AMP + D-ribose 5-phosphate	-	?
IDP-ribose + H2O	-	Rattus norvegicus	IMP + ribose 5-phosphate	-	?
IDP-ribose + H2O	77% of the activity with ADPribose	Artemia sp.	IMP + ribose 5-phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)