3.5.2.3: dihydroorotase

This is an abbreviated version!
For detailed information about dihydroorotase, go to the full flat file.

Word Map on EC 3.5.2.3

3.5.2.3

pyrimidine

transcarbamoylase

carbamoyl-phosphate

phosphoribosyltransferase

atcase

orotidine

carbamoyltransferase

glutamine-dependent

l-dihydroorotate

2.1.3.2

cpsase

pyre

dihydropyrimidinase

hydantoinase

dihydro-ouabain

n-phosphonacetyl-l-aspartate

n-carbamyl-l-aspartate

allantoinase

imidase

synthesis

succinate-grown

amidohydrolases

6.3.5.5

drug development

medicine

5-fluoroorotate

Reaction

Synonyms

amidohydrolase family protein, BcDHOase, CAD, carbamoylaspartic dehydrase, Class I DHOase, DHO, DHOase, dihydroorotase, dihydroorotase domain, dihydroorotate dehydrolase, hDHOase, huDHOase, human DHOase domain, LdDHOase, More, pyrC, type I DHOase, type II DHO, VcDHO, YpDHO

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.2 In cyclic amides

3.5.2.3 dihydroorotase

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Results	in table
5	Activating Compound
46170	AA Sequence
9	Application
1	CAS Registry Number
35	Cloned(Commentary)
17	Crystallization (Commentary)
71	Disease/ Diagnostics
48	General Information
8	IC50 Value
93	Inhibitors
15	kcat/KM [mM/s]
28	Ki Value [mM]
74	KM Value [mM]
1	Localization
27	Metals/Ions
41	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
91	Organism
7	Pathway
143	PDB ID
18	pH Optimum
5	pH Range
1	pH Stability
3	pI Value
3	Posttranslational Modification
48	Protein Variants
44	Purification (Commentary)
4	Reaction
3	Reaction Type
89	Reference
17	Source Tissue
18	Specific Activity [micromol/min/mg]
11	Storage Stability
105	Substrates and Products (Substrate)
51	Subunits
89	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
6	Temperature Range [°C]
8	Temperature Stability [°C]
29	Turnover Number [1/s]

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1.1 - 1.9

(S)-dihydroorotate

4 entries

127

dihydro-DL-orotate

Escherichia coli

246634

0.653

L-carbamoylaspartate

2 entries

0.183 - 4.31

L-dihydroorotate

4 entries

0.073 - 181.1

N-(aminocarbonyl)-L-aspartic acid

6 entries

195

N-carbamoyl-DL-aspartate

Escherichia coli

246634

1.4 - 62.3

N-carbamoyl-L-aspartate

11 entries