3.5.2.3: dihydroorotase
This is an abbreviated version!
For detailed information about dihydroorotase, go to the full flat file.
Word Map on EC 3.5.2.3
-
3.5.2.3
-
pyrimidine
-
transcarbamoylase
-
carbamoyl-phosphate
-
phosphoribosyltransferase
-
atcase
-
orotidine
-
carbamoyltransferase
-
glutamine-dependent
-
l-dihydroorotate
-
2.1.3.2
-
cpsase
-
pyre
-
dihydropyrimidinase
-
hydantoinase
-
dihydro-ouabain
-
n-phosphonacetyl-l-aspartate
-
n-carbamyl-l-aspartate
-
allantoinase
-
imidase
-
synthesis
-
succinate-grown
-
amidohydrolases
-
6.3.5.5
-
drug development
-
medicine
-
5-fluoroorotate
- 3.5.2.3
- pyrimidine
-
transcarbamoylase
- carbamoyl-phosphate
- phosphoribosyltransferase
- atcase
- orotidine
-
carbamoyltransferase
-
glutamine-dependent
- l-dihydroorotate
-
2.1.3.2
- cpsase
-
pyre
- dihydropyrimidinase
- hydantoinase
- dihydro-ouabain
- n-phosphonacetyl-l-aspartate
-
n-carbamyl-l-aspartate
- allantoinase
- imidase
- synthesis
-
succinate-grown
-
amidohydrolases
-
6.3.5.5
- drug development
- medicine
- 5-fluoroorotate
Reaction
Synonyms
amidohydrolase family protein, BcDHOase, CAD, carbamoylaspartic dehydrase, Class I DHOase, DHO, DHOase, dihydroorotase, dihydroorotase domain, dihydroorotate dehydrolase, hDHOase, huDHOase, human DHOase domain, LdDHOase, More, pyrC, type I DHOase, type II DHO, VcDHO, YpDHO
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KI Value
KI Value on EC 3.5.2.3 - dihydroorotase
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2.3
(S)-1,2,3,6-tetrahydro-6-oxopyridine-2-carboxylic acid
-
with thio-dihydroorotate as substrate, pH. 8.0
1.6
4(R)-hydroxy-6-oxo-piperidine-2(S)-carboxylic acid
-
with thio-dihydroorotate as substrate, pH. 8.0
3
4(S)-hydroxy-6-oxo-piperidine-2(S)-carboxylic acid
-
with thio-dihydroorotate as substrate, pH. 8.0
0.0045
-
at 37°C
0.083
2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylic acid
-
at 37°C
0.102
2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylic acid
-
at 60°C
0.076
-
with dihydroorotate as substrate, pH. 7.0
0.096
4,6-dioxo-piperidine-2-(S)-carboxylic acid
-
with thio-dihydroorotate as substrate, pH. 7.0
0.12
4,6-dioxo-piperidine-2-(S)-carboxylic acid
-
with thio-dihydroorotate as substrate, pH. 8.0
0.21
4,6-dioxo-piperidine-2-(S)-carboxylic acid
-
with dihydroorotate as substrate, pH. 8.0
0.32
4,6-dioxo-piperidine-2-(S)-carboxylic acid
-
with thio-dihydroorotate as substrate, pH. 9.0
0.44
4,6-dioxo-piperidine-2-(S)-carboxylic acid
-
with dihydroorotate as substrate, pH. 9.0