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3.5.2.3: dihydroorotase

This is an abbreviated version!
For detailed information about dihydroorotase, go to the full flat file.

Word Map on EC 3.5.2.3

Reaction

(S)-dihydroorotate
+
H2O
=
N-carbamoyl-L-aspartate

Synonyms

amidohydrolase family protein, BcDHOase, CAD, carbamoylaspartic dehydrase, Class I DHOase, DHO, DHOase, dihydroorotase, dihydroorotase domain, dihydroorotate dehydrolase, hDHOase, huDHOase, human DHOase domain, LdDHOase, More, pyrC, type I DHOase, type II DHO, VcDHO, YpDHO

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.2 In cyclic amides
                3.5.2.3 dihydroorotase

IC50 Value

IC50 Value on EC 3.5.2.3 - dihydroorotase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.16
Cd2+
Klebsiella pneumoniae
pH 9.0, 25°C
0.15
Co2+
Klebsiella pneumoniae
pH 9.0, 25°C
0.031
kaempferol
Klebsiella pneumoniae
-
pH 8.0, 25°C, recombinant enzyme
0.24
Mn2+
Klebsiella pneumoniae
pH 9.0, 25°C
0.04
myricetin
Klebsiella pneumoniae
-
pH 8.0, 25°C, recombinant enzyme
3.29
Ni2+
Klebsiella pneumoniae
pH 9.0, 25°C
200
phosphate
Klebsiella pneumoniae
pH 9.0, 25°C
0.19
Zn2+
Klebsiella pneumoniae
pH 9.0, 25°C