3.4.24.28: bacillolysin

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For detailed information about bacillolysin, go to the full flat file.

Word Map on EC 3.4.24.28

3.4.24.28

calcium-activated

calpain

hydrolysates

alcalase

collagenase

collagen

ca2+-activated

mast

elastase

leupeptin

casein

flavourzyme

pepsin

protamex

calcium-dependent

ultrafiltration

ca2+-dependent

tryptase

metalloprotease

calpastatin

chymase

stearothermophilus

dispase

autolysis

cereus

1,1-diphenyl-2-picrylhydrazyl

amyloliquefaciens

neurofilament

2,2-diphenyl-1-picrylhydrazyl

myofibril

npr

spectrin

antipain

bromelain

ace-inhibitory

pancreases

calpain-mediated

i-converting

calpeptin

synthesis

medicine

food industry

Reaction

similar, but not identical, to that of thermolysin =

Synonyms

Anilozyme P 10, bacillolysin, bacillolysin-neutral protease, Bacillus metalloendopeptidase, Bacillus metalloproteinase, Bacillus neutral proteinase, Bacillus polymyxa protease, Bacillus pumilus metalloendopeptidase, Bacillus subtilis neutral protease, Bacillus subtilis neutral proteinase, Bae16, BL-MA, BMP1, C histolyticum neutral protease, CHNP, EC 3.4.24.4, MCP 76, Megateriopeptidase, metallo-neutral protease, MprBi, mprBp, Neutral protease, neutrase, non-specific neutral protease, protease N, thermolysin-like enzyme, Thermostable neutral protease, thermoysin-like proteinase, TLP-ste, TLP-sub

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.28 bacillolysin

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Results	in table
3	Activating Compound
150	AA Sequence
6	Application
1	CAS Registry Number
9	Cloned(Commentary)
2	Crystallization (Commentary)
2	Expression
7	General Information
4	General Stability
42	Inhibitors
3	Ki Value [mM]
8	KM Value [mM]
5	Localization
21	Metals/Ions
15	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
12	Organic Solvent Stability
44	Organism
1	PDB ID
8	pH Optimum
7	pH Range
11	pH Stability
1	pI Value
6	Protein Variants
12	Purification (Commentary)
1	Reaction
1	Reaction Type
44	Reference
2	Renatured (Commentary)
6	Source Tissue
22	Specific Activity [micromol/min/mg]
81	Substrates and Products (Substrate)
11	Subunits
39	Synonyms
17	Temperature Optimum [°C]
5	Temperature Range [°C]
17	Temperature Stability [°C]
6	Turnover Number [1/s]

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Engineering on EC 3.4.24.28 - bacillolysin

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Go to Protein Variants Search

I157D

Bacillus subtilis

site-directed mutagenesis

650655

G8C/N60C

4 entries

W55F

Geobacillus stearothermophilus

higher Ca2+ concentration is needed than for wild-type for occupation of Ca2+-binding site III at amino acids 55-59

668546