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3.4.24.28: bacillolysin

This is an abbreviated version!
For detailed information about bacillolysin, go to the full flat file.

Word Map on EC 3.4.24.28

Reaction

similar, but not identical, to that of thermolysin =

Synonyms

Anilozyme P 10, bacillolysin, bacillolysin-neutral protease, Bacillus metalloendopeptidase, Bacillus metalloproteinase, Bacillus neutral proteinase, Bacillus polymyxa protease, Bacillus pumilus metalloendopeptidase, Bacillus subtilis neutral protease, Bacillus subtilis neutral proteinase, Bae16, BL-MA, BMP1, C histolyticum neutral protease, CHNP, EC 3.4.24.4, MCP 76, Megateriopeptidase, metallo-neutral protease, MprBi, mprBp, Neutral protease, neutrase, non-specific neutral protease, protease N, thermolysin-like enzyme, Thermostable neutral protease, thermoysin-like proteinase, TLP-ste, TLP-sub

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.28 bacillolysin

Inhibitors

Inhibitors on EC 3.4.24.28 - bacillolysin

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
94.2% inhibition at 0.5 mM, 100% at 5 mM
2-mercaptoethanol
-
27% inhibition at 50 mM
Ba2+
-
88% inhibition at 10 mM
Ca2+
30-40% inhibition at 4-8 mM
dithio-bis-nitrobenzoic acid
-
64% inhibition at 50 mM
dithiothreitol
Fe2+
-
86% inhibition at 10 mM
Fe3+
-
98% inhibition at 10 mM
guanidine hydrochloride
-
competitive inhibitor
HgCl2
49% inhibition at 0.5 mM, 60% at 5 mM
Mg2+
72% inhibition at 4-8 mM
Mn2+
64% inhibition at 4-8 mM
N-[alpha-L-rhamnopyranosyl-oxyhydroxyphosphinyl]-L-leucyl-L-tryptophan
-
-
organic solvents
-
and related compounds, overview
-
PCMB
6% inhibition at 0.5 mM, 98.1% at 5 mM
pepstatin A
slight inhibition
phenylmethylsulfonyl fluoride
-
0.1 mM, 77% residual activity
SDS
-
37% inhibition at 50 mM
Triton X-100
-
slight inhibition at 50 mM
additional information
-