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3.4.24.28: bacillolysin

This is an abbreviated version!
For detailed information about bacillolysin, go to the full flat file.

Word Map on EC 3.4.24.28

Reaction

similar, but not identical, to that of thermolysin =

Synonyms

Anilozyme P 10, bacillolysin, bacillolysin-neutral protease, Bacillus metalloendopeptidase, Bacillus metalloproteinase, Bacillus neutral proteinase, Bacillus polymyxa protease, Bacillus pumilus metalloendopeptidase, Bacillus subtilis neutral protease, Bacillus subtilis neutral proteinase, Bae16, BL-MA, BMP1, C histolyticum neutral protease, CHNP, EC 3.4.24.4, MCP 76, Megateriopeptidase, metallo-neutral protease, MprBi, mprBp, Neutral protease, neutrase, non-specific neutral protease, protease N, thermolysin-like enzyme, Thermostable neutral protease, thermoysin-like proteinase, TLP-ste, TLP-sub

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.28 bacillolysin

Reference

topprint

Reference on EC 3.4.24.28 - bacillolysin

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Holmquist, B.; Vallee, B.L.
Esterase activity of zinc neutral proteases
Biochemistry
15
101-107
1976
Bacillus subtilis
Manually annotated by BRENDA team
Morihara, K.; Tsuzuki, H.; Oka, T.
Comparison of the specificities of various neutral proteinases from microorganisms
Arch. Biochem. Biophys.
123
572-588
1968
Bacillus subtilis
Manually annotated by BRENDA team
Holland, D.R.; Tronrud, D.E.; Pley, H.W.; Flaherty, K.M.; Stark, W.; Jansonius, J.N.; McKay, D.B.; Matthews, B.W.
Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis
Biochemistry
31
11310-11316
1992
Bacillus cereus
Manually annotated by BRENDA team
Sidler, W.; Niederer, E.; Suter, F.; Zuber, H.
The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase
Biol. Chem. Hoppe-Seyler
367
643-657
1986
Bacillus cereus, Bacillus subtilis
Manually annotated by BRENDA team
Vasantha, N.; Thompson, L.D.; Rhodes, C.; Banner, C.; Nagle, J.; Filpula, D.
Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein
J. Bacteriol.
159
811-819
1984
Bacillus amyloliquefaciens
Manually annotated by BRENDA team
Takagi, M.; Imanaka, T.; Aiba, S.
Nucleotide sequence and promoter region for the neutral protease gene from Bacillus stearothermophilus
J. Bacteriol.
163
824-831
1985
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Stoeva, S.; Kleinschmidt, T.; Mesrob, B.; Braunitzer, G.
Primary structure of a zinc protease from Bacillus mesentericus strain 76
Biochemistry
29
527-534
1990
Bacillus pumilus, Bacillus pumilus 76
Manually annotated by BRENDA team
Pauptit, R.A.; Kalsson, R.; Picot, D.; Jenkins, J.A.; Niklaus-Reimer, A.S.; Jansonius, J.N.
Crystal structure of neutral protease from Bacillus cereus refined at 3.0 A resolution and comparison with the homologous but more thermostable enzyme thermolysin
J. Mol. Biol.
199
525-537
1988
Bacillus cereus
Manually annotated by BRENDA team
Feder, J.; Keay, L.; Garrett, L.R.; Cirulis, N.; Moseley, M.H.; Wildi, B.S.
Bacillus cereus neutral protease
Biochim. Biophys. Acta
251
74-78
1971
Bacillus cereus
Manually annotated by BRENDA team
Millet, J.; Acher, R.
Specificity of megateriopeptidase: an amino-endopeptidase with hydrophobic characteristics
Eur. J. Biochem.
9
456-462
1969
Priestia megaterium
Manually annotated by BRENDA team
Yang, M.Y.; Ferrari, E.; Henner, D.J.
Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation
J. Bacteriol.
160
15-21
1984
Bacillus subtilis
Manually annotated by BRENDA team
Tsuru, D.; Imajo, S.; Morikawa, S.; Yoshimoto, T.; Ishiguro, M.
Zinc protease of Bacillus subtilis var. amylosacchariticus: construction of a three-dimensional model and comparison with thermolysin
J. Biochem.
113
101-105
1993
Bacillus subtilis
Manually annotated by BRENDA team
Sidler, W.; Zuber, H.
Isolation procedures for thermostable neutral proteinases produced by Bacillus stearothermophilus
Eur. J. Appl. Microbiol. Biotechnol.
10
197-209
1980
Geobacillus stearothermophilus
-
Manually annotated by BRENDA team
Sidler, W.; Zuber, H.
Neutral proteases with different thermostabilities from a facultative strain of Bacillus stearothermophilus grown at 40.deg. and at 50.deg
FEBS Lett.
25
292-294
1972
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Paberit, N.; Paberit, M.
Inhibition of thermolysin and Bacillus brevis neutral proteinase by organic solvents and some related compounds
Quant. Struct. -Act. Relat.
11
28-33
1992
Brevibacillus brevis
-
Manually annotated by BRENDA team
Van den Burg, B.; Eijsink, V.G.H.; Vriend, G.; Veltman, O.R.; Venema, G.
Rendering one autolysis site in Bacillus subtilis neutral protease resistant to cleavage reveals a new fission
Biotechnol. Appl. Biochem.
27
125-132
1998
Bacillus subtilis
-
Manually annotated by BRENDA team
Duerrschmidt, P.; Mansfeld, J.; Ulbrich-Hofmann, R.
Differentiation between conformational and autoproteolytic stability of the neutral protease from Bacillus stearothermophilus containing an engineered disulfide bond
Eur. J. Biochem.
268
3612-3618
2001
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Niu, Q.; Huang, X.; Zhang, L.; Li, Y.; Li, J.; Yang, J.; Zhang, K.
A neutral protease from Bacillus nematocida, another potential virulence factor in the infection against nematodes
Arch. Microbiol.
185
439-448
2006
Bacillus nematocida
Manually annotated by BRENDA team
Duerrschmidt, P.; Mansfeld, J.; Ulbrich-Hofmann, R.
An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding
FEBS J.
272
1523-1534
2005
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Narasaki, R.; Kuribayashi, H.; Shimizu, K.; Imamura, D.; Sato, T.; Hasumi, K.
Bacillolysin MA, a novel bacterial metalloproteinase that produces angiostatin-like fragments from plasminogen and activates protease zymogens in the coagulation and fibrinolysis systems
J. Biol. Chem.
280
14278-14287
2005
Priestia megaterium, Priestia megaterium A9542
Manually annotated by BRENDA team
Mansfeld, J.; Petermann, E.; Duerrschmidt, P.; Ulbrich-Hofmann, R.
The propeptide is not required to produce catalytically active neutral protease from Bacillus stearothermophilus
Protein Expr. Purif.
39
219-228
2005
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Mansfeld, J.; Ulbrich-Hofmann, R.
The stability of engineered thermostable neutral proteases from Bacillus stearothermophilus in organic solvents and detergents
Biotechnol. Bioeng.
97
672-679
2007
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Albillos, S.M.; Busto, M.D.; Perez-Mateos, M.; Ortega, N.
Analysis by capillary electrophoresis of the proteolytic activity of a Bacillus subtilis neutral protease on bovine caseins
Int. Dairy J.
17
1195-1200
2007
Bacillus subtilis
Manually annotated by BRENDA team
Zhang, M.; Zhao, C.; Du, L.; Lu, F.; Gao, C.
Expression, purification, and characterization of a thermophilic neutral protease from Bacillus stearothermophilus in Bacillus subtilis
Sci. China C Life Sci.
51
52-59
2008
Geobacillus stearothermophilus (P43133), Geobacillus stearothermophilus
Manually annotated by BRENDA team
Duerrschmidt, P.; Mansfeld, J.; Ulbrich-Hofmann, R.
Refolding of the non-specific neutral protease from Bacillus stearothermophilus proceeds via an autoproteolytically sensitive intermediate
Biophys. Chem.
147
66-73
2010
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Rudakova, N.L.; Balaban, N.P.; Danilova, Y.V.; Rudenskaya, G.N.; Sharipova, M.R.
Characteristics of a novel secreted zinc-dependent endopeptidase of Bacillus intermedius
Biochemistry (Moscow)
75
1294-1301
2010
Bacillus intermedius (B3V4Z0), Bacillus intermedius
Manually annotated by BRENDA team
Niu, Q.; Tian, Y.; Zhang, L.; Xu, X.; Niu, X.; Xia, Z.; Lei, L.; Zhang, K.Q.; Huang, X.
Overexpression of the key virulence proteases Bace16 and Bae16 in Bacillus nematocida B16 to improve its nematocidal activity
J. Mol. Microbiol. Biotechnol.
21
130-137
2011
Paenibacillus polymyxa, Hathewaya histolytica
Manually annotated by BRENDA team
Wang, J.; Xu, A.; Wan, Y.; Li, Q.
Purification and characterization of a new metallo-neutral protease for beer brewing from Bacillus amyloliquefaciens SYB-001
Appl. Biochem. Biotechnol.
170
2021-2033
2013
Bacillus amyloliquefaciens, Bacillus amyloliquefaciens SYB-001
Manually annotated by BRENDA team
Luo, X.; Chen, L.; Huang, Q.; Zheng, J.; Zhou, W.; Peng, D.; Ruan, L.; Sun, M.
Bacillus thuringiensis metalloproteinase Bmp1 functions as a nematicidal virulence factor
Appl. Environ. Microbiol.
79
460-468
2013
Bacillus thuringiensis (L0AQH5), Bacillus thuringiensis, Bacillus thuringiensis YBT-1518 (L0AQH5)
Manually annotated by BRENDA team
Saxena, R.; Singh, R.
MALDI-TOF MS and CD spectral analysis for identification and structure prediction of a purified, novel, organic solvent stable, fibrinolytic metalloprotease from Bacillus cereus B80
BioMed Res. Int.
2015
527015
2015
Bacillus cereus, Bacillus cereus B80
Manually annotated by BRENDA team
Zhu, M.; Cheng, J.; Chen, H.; Deng, M.; Xie, W.
Optimization of neutral protease production from Bacillus subtilis: Using agroindustrial residues as substrates and response surface methodology
Biotechnol. Appl. Biochem.
60
336-342
2013
Bacillus subtilis, Bacillus subtilis DES-59
Manually annotated by BRENDA team
Guinane, C.; Kent, R.; Norberg, S.; O'Connor, P.; Cotter, P.; Hill, C.; Fitzgerald, G.; Stanton, C.; Ross, R.
Generation of the antimicrobial peptide caseicin A from casein by hydrolysis with thermolysin enzymes
Int. Dairy J.
49
1-7
2015
Bacillus subtilis
-
Manually annotated by BRENDA team
Hatta, E.; Matsumoto, K.; Honda, Y.
Bacillolysin, papain, and subtilisin improve the quality of gluten-free rice bread
J. Cereal Sci.
61
41-47
2015
Bacillus amyloliquefaciens
-
Manually annotated by BRENDA team
Rudakova, N.L.; Sabirova, A.R.; Balaban, N.P.; Tikhonova, A.O.; Sharipova, M.R.
Features of gene expression of Bacillus pumilus metalloendopeptidase
Biochemistry (Moscow)
81
884-891
2016
Bacillus pumilus
Manually annotated by BRENDA team
Erban, T.; Rybanska, D.; Harant, K.; Hortova, B.; Hubert, J.
Feces derived allergens of tyrophagus putrescentiae reared on dried dog food and evidence of the strong nutritional interaction between the mite and bacillus cereus producing protease bacillolysins and exo-chitinases
Front. Physiol.
7
53
2016
Bacillus cereus
Manually annotated by BRENDA team
Bavaro, T.; Cattaneo, G.; Serra, I.; Benucci, I.; Pregnolato, M.; Terreni, M.
Immobilization of neutral protease from Bacillus subtilis for regioselective hydrolysis of acetylated nucleosides application to capecitabine synthesis
Molecules
21
E1621
2016
Bacillus subtilis
Manually annotated by BRENDA team