3.4.22.B73: SENP5 peptidase
This is an abbreviated version!
For detailed information about SENP5 peptidase, go to the full flat file.
Word Map on EC 3.4.22.B73
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3.4.22.B73
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senps
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desumoylation
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deconjugation
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isopeptidase
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mitosis
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fission
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nucleolus
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regulator-related
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medicine
- 3.4.22.B73
-
senps
-
desumoylation
-
deconjugation
- isopeptidase
-
mitosis
-
fission
- nucleolus
-
regulator-related
- medicine
Reaction
SENP5 additional information efficiently removes SUMO-2 and SUMO-3 than SUMO-1 from SUMO-modified target such as Ran GTPase-activating protein 1. Catalyzes desumoylation of mitochondrial fission GTPase DRP1. =
Synonyms
SENP5, SENP5 peptidase, sentrin/small ubiquitin-like modifier-specific protease5, SUMO isopeptidase, SUMO-specific protease 5
ECTree
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Cloned
Cloned on EC 3.4.22.B73 - SENP5 peptidase
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transgenic overexpression of SENP5 in murine cardiomyocytes, overexpression of SENP5 leads to cardiac dysfunction, accompanied by decreased cardiomyocyte proliferation and elevated apoptosis
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