3.4.22.B73: SENP5 peptidase
This is an abbreviated version!
For detailed information about SENP5 peptidase, go to the full flat file.
Word Map on EC 3.4.22.B73
-
3.4.22.B73
-
senps
-
desumoylation
-
deconjugation
-
isopeptidase
-
mitosis
-
fission
-
nucleolus
-
regulator-related
-
medicine
- 3.4.22.B73
-
senps
-
desumoylation
-
deconjugation
- isopeptidase
-
mitosis
-
fission
- nucleolus
-
regulator-related
- medicine
Reaction
SENP5 additional information efficiently removes SUMO-2 and SUMO-3 than SUMO-1 from SUMO-modified target such as Ran GTPase-activating protein 1. Catalyzes desumoylation of mitochondrial fission GTPase DRP1. =
Synonyms
SENP5, SENP5 peptidase, sentrin/small ubiquitin-like modifier-specific protease5, SUMO isopeptidase, SUMO-specific protease 5
ECTree
Advanced search results
Localization
Localization on EC 3.4.22.B73 - SENP5 peptidase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
-
SENP5 expression is chiefly detected in the cytoplasm of tumor cells and in the cytoplasm and/or nucleus of normal epithelium cells
Senp5 is localized to presynaptic terminals, postsynaptic spines, and mitochondria in axon terminals
-
in interphase, SenP5 resides primarily within the nucleoli, in addition to a cytosolic pool. Relocalization of SenP5 from the nucleoli to the mitochondrial surface at G2/M transition prior to nuclear envelope breakdown
-
in interphase, SenP5 resides primarily within the nucleoli, in addition to a cytosolic pool. Relocalization of SenP5 from the nucleoli to the mitochondrial surface at G2/M transition prior to nuclear envelope breakdown. Transition of SenP5 to the mitochondria plays an important role in mitochondrial fragmentation during mitosis
Senp5 is localized to presynaptic terminals, postsynaptic spines, and mitochondria in axon terminals
-
in interphase, SenP5 resides primarily within the nucleoli, in addition to a cytosolic pool. Relocalization of SenP5 from the nucleoli to the mitochondrial surface at G2/M transition prior to nuclear envelope breakdown
-
SENP5 expression is chiefly detected in the cytoplasm of tumor cells and in the cytoplasm and/or nucleus of normal epithelium cells
-
SENP5 localizes within the granular component of the nucleolus, a subnucleolar compartment that contains B23/nucleophosmin