3.4.22.B73: SENP5 peptidase

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For detailed information about SENP5 peptidase, go to the full flat file.

Reaction

SENP5 additional information efficiently removes SUMO-2 and SUMO-3 than SUMO-1 from SUMO-modified target such as Ran GTPase-activating protein 1. Catalyzes desumoylation of mitochondrial fission GTPase DRP1. =

Synonyms

SENP5, SENP5 peptidase, sentrin/small ubiquitin-like modifier-specific protease5, SUMO isopeptidase, SUMO-specific protease 5

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.B73 SENP5 peptidase

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Results	in table
1	Activating Compound
2	AA Sequence
2	Application
2	Cloned(Commentary)
75	Disease/ Diagnostics
12	General Information
13	Localization
3	Natural Substrates/ Products (Substrates)
10	Organism
1	Protein Variants
1	Purification (Commentary)
1	Reaction
10	Reference
8	Source Tissue
10	Substrates and Products (Substrate)
8	Synonyms

Activating Compound

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Activating Compound on EC 3.4.22.B73 - SENP5 peptidase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

B23/nucleophosmin

Homo sapiens

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B23/nucleophosmin physically interacts with SENP3 and SENP5 and regulates their abundance. It thus plays a critical role in controlling the profile of SUMO conjugates within nucleoli through SENP3 and SENP5

715705

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