3.4.22.B73: SENP5 peptidase

This is an abbreviated version!
For detailed information about SENP5 peptidase, go to the full flat file.

Word Map on EC 3.4.22.B73

3.4.22.B73

senps

desumoylation

deconjugation

isopeptidase

mitosis

fission

nucleolus

regulator-related

medicine

Reaction

SENP5 additional information efficiently removes SUMO-2 and SUMO-3 than SUMO-1 from SUMO-modified target such as Ran GTPase-activating protein 1. Catalyzes desumoylation of mitochondrial fission GTPase DRP1. =

Synonyms

SENP5, SENP5 peptidase, sentrin/small ubiquitin-like modifier-specific protease5, SUMO isopeptidase, SUMO-specific protease 5

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.B73 SENP5 peptidase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
1	Activating Compound
2	AA Sequence
2	Application
2	Cloned(Commentary)
75	Disease/ Diagnostics
12	General Information
13	Localization
3	Natural Substrates/ Products (Substrates)
10	Organism
1	Protein Variants
1	Purification (Commentary)
1	Reaction
10	Reference
8	Source Tissue
10	Substrates and Products (Substrate)
8	Synonyms

Disease

top print

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Disease on EC 3.4.22.B73 - SENP5 peptidase

Please use the Disease Search for a specific query.

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Breast Neoplasms

SENP5 mediates breast cancer invasion via a TGF?RI SUMOylation cascade.

24658161

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656

Carcinogenesis

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656

Carcinoma

Inhibition of SENP5 suppresses cell growth and promotes apoptosis in osteosarcoma cells.

24926368

Overexpression of SENP5 in oral squamous cell carcinoma and its association with differentiation.

18949399

Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis.

25901414

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656

Carcinoma, Hepatocellular

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656

Cardiomyopathies

SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy.

25128087

Cardiomyopathy, Dilated

SUMOylation in cardiac disorders - a review.

28429347

Epilepsy

SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.

34313310

Glioblastoma

SUMOylation Regulator-Related Molecules Can Be Used as Prognostic Biomarkers for Glioblastoma.

33898460

Heart Failure

SUMOylation in cardiac disorders - a review.

28429347

Muscular Diseases

SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy.

25128087

Neoplasms

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656

Osteosarcoma

Inhibition of SENP5 suppresses cell growth and promotes apoptosis in osteosarcoma cells.

24926368

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656

Squamous Cell Carcinoma of Head and Neck

Inhibition of SENP5 suppresses cell growth and promotes apoptosis in osteosarcoma cells.

24926368

Overexpression of SENP5 in oral squamous cell carcinoma and its association with differentiation.

18949399

Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis.

25901414

The SUMO-specific protease SENP5 controls DNA damage response and promotes tumorigenesis in hepatocellular carcinoma.

27649656