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3.4.22.43: cathepsin V

This is an abbreviated version!
For detailed information about cathepsin V, go to the full flat file.

Word Map on EC 3.4.22.43

Reaction

The recombinant enzyme hydrolyses proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-Arg-NHMec) =

Synonyms

cathepsin L2, cathepsin L2/V, cathepsin like 2, cathepsin U, cathepsin V, cathepsin V/L2, cathepsin-V, CatV, CL2, CTSL2, CTSV, CV/L2, hcatV, More, stratum corneum thiol protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.43 cathepsin V

Crystallization

Crystallization on EC 3.4.22.43 - cathepsin V

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
cathepsin V in complex with clitocypin, vapor diffusion method, using 0.4 M Li2SO4, 12% (w/v) polyethylene glycol 800, 20% (v/v) glycerol
molecular modeling of complex with fragment p41 of major histocompatibility complex class II-associated invariant chain
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space group P6422, crystal structure at 1.6 A resolution
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