3.4.22.43: cathepsin V
This is an abbreviated version!
For detailed information about cathepsin V, go to the full flat file.
Word Map on EC 3.4.22.43
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3.4.22.43
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cathepsins
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papain-like
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elastases
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elastolytic
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legumain
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l-like
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medicine
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diagnostics
- 3.4.22.43
- cathepsins
-
papain-like
- elastases
-
elastolytic
- legumain
-
l-like
- medicine
- diagnostics
Reaction
The recombinant enzyme hydrolyses proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-Arg-NHMec) =
Synonyms
cathepsin L2, cathepsin L2/V, cathepsin like 2, cathepsin U, cathepsin V, cathepsin V/L2, cathepsin-V, CatV, CL2, CTSL2, CTSV, CV/L2, hcatV, More, stratum corneum thiol protease
ECTree
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KCat KM Value
KCat KM Value on EC 3.4.22.43 - cathepsin V
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496
2-aminobenzoyl-KPPVVLLPDQ-N-[2,4-dinitrophenyl]ethylenediamine
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at 37°C, in 0.1 M sodium acetate buffer, pH 5.5
903
2-aminobenzoyl-KPVSTEQLAQ-N-[2,4-dinitrophenyl]ethylenediamine
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at 37°C, in 0.1 M sodium acetate buffer, pH 5.5
4528
2-aminobenzoyl-LFEKQ-N-[2,4-dinitrophenyl]ethylenediamine
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at 37°C, in 0.1 M sodium acetate buffer, pH 5.5
3055
2-aminobenzoyl-VLFEKKQ-N-[2,4-dinitrophenyl]ethylenediamine
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at 37°C, in 0.1 M sodium acetate buffer, pH 5.5
6833
2-aminobenzoyl-VLFEKKVYLQ-N-[2,4-dinitrophenyl]ethylenediamine
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at 37°C, pH 5.5
4277
2-aminobenzoyl-VLFEKQ-N-[2,4-dinitrophenyl]ethylenediamine
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at 37°C, in 0.1 M sodium acetate buffer, pH 5.5
35000
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
in 0.1 M sodium acetate buffer pH 5.5 containing 2.5 mM dithiothreitol and 1 mM EDTA, at 25°C
7900
benzyloxycarbonyl-Val-Val-Arg-7-amido-4-methylcoumarin
in 0.1 M sodium acetate buffer pH 5.5 containing 2.5 mM dithiothreitol and 1 mM EDTA, at 25°C