3.4.22.43: cathepsin V

This is an abbreviated version!
For detailed information about cathepsin V, go to the full flat file.

Word Map on EC 3.4.22.43

3.4.22.43

cathepsins

papain-like

elastases

elastolytic

legumain

l-like

medicine

diagnostics

Reaction

The recombinant enzyme hydrolyses proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-Arg-NHMec) =

Synonyms

cathepsin L2, cathepsin L2/V, cathepsin like 2, cathepsin U, cathepsin V, cathepsin V/L2, cathepsin-V, CatV, CL2, CTSL2, CTSV, CV/L2, hcatV, More, stratum corneum thiol protease

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.43 cathepsin V

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Results	in table
1	Activating Compound
12	AA Sequence
3	Application
1	CAS Registry Number
17	Cloned(Commentary)
3	Crystallization (Commentary)
127	Disease/ Diagnostics
6	Expression
14	General Information
16	IC50 Value
63	Inhibitors
8	kcat/KM [mM/s]
17	Ki Value [mM]
13	KM Value [mM]
11	Localization
1	Metals/Ions
15	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
37	Organism
6	PDB ID
9	pH Optimum
3	pH Range
6	pH Stability
6	Posttranslational Modification
4	Protein Variants
6	Purification (Commentary)
2	Reaction
1	Reaction Type
37	Reference
86	Source Tissue
5	Specific Activity [micromol/min/mg]
64	Substrates and Products (Substrate)
8	Subunits
33	Synonyms
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
13	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 3.4.22.43 - cathepsin V

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23000

Homo sapiens

x * 23000, nonglycosylated form, SDS-PAGE

717159

23999

Homo sapiens

2 * 23999, amino acid sequence calculation of the mature enzyme, 2 * 31000, recombinant mature enzyme from insect cells and Pichia pastoris, 2 * 38000-45000, recombinant proenzyme from Pichi pastoris

668763

24000

2 entries

31000

Homo sapiens

2 * 23999, amino acid sequence calculation of the mature enzyme, 2 * 31000, recombinant mature enzyme from insect cells and Pichia pastoris, 2 * 38000-45000, recombinant proenzyme from Pichi pastoris

35000

35500

proprotein, SDS-PAGE

37000

37330

preproprotein, containing a 17 amino acid signal peptide, a 96 amino acid propeptide and a 221 amino acid mature region, calculation from sequence of cDNA

137269

39000

Homo sapiens

glycosylated enzyme form, SDS-PAGE

137270

41000

Homo sapiens

glycosylated enzyme form, SDS-PAGE

137270

42151

Lepeophtheirus salmonis

A7TZ36

x * 42151, calculated from amino acid sequence

731213

52000

Homo sapiens

recombinant GST-tagged enzyme

668763