3.4.21.B57: pernisine

This is an abbreviated version!
For detailed information about pernisine, go to the full flat file.

the enzyme can digest the pathological prion protein isoform (PrPSc) from different species, e.g. human, bovine, deer and mouse =

pernisine, subtilase, Tk-SP, Tk-subtilisin, TKS

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
4	Activating Compound
2	AA Sequence
4	Application
11	Cloned(Commentary)
7	Crystallization (Commentary)
1	Expression
3	General Information
13	General Stability
28	Inhibitors
1	Ki Value [mM]
2	KM Value [mM]
5	Localization
10	Metals/Ions
14	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
13	Organic Solvent Stability
38	Organism
10	pH Optimum
4	pH Range
13	Posttranslational Modification
16	Protein Variants
9	Purification (Commentary)
1	Reaction
22	Reference
2	Specific Activity [micromol/min/mg]
36	Substrates and Products (Substrate)
12	Subunits
19	Synonyms
11	Temperature Optimum [°C]
4	Temperature Range [°C]
23	Temperature Stability [°C]
2	Turnover Number [1/s]

pH Range on EC 3.4.21.B57 - pernisine

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

3 - 10

active between pH 3.0 and pH 10.0, in the presence of 1 mM CaCl2, at 92°C

3.5 - 8

active between pH 3.5 and pH 8.0, in absence of CaCl2, at 92°C

4.5 - 9.1

the recombinant enzyme shows more than 90% activity within this pH range

6 - 12

pH 6.0: about 50% of maximal activity, pH 12.0: about 40% of maximal activity