3.4.21.B57: pernisine

This is an abbreviated version!
For detailed information about pernisine, go to the full flat file.

Word Map on EC 3.4.21.B57

3.4.21.B57

hyperthermophilic

archaeon

subtilisin-like

pernix

aeropyrum

subtilisins

thermococcus

prion

medicine

kodakaraensis

proregion

mesophilic

autoprocessed

detergents

edta

codon-optimised

far-uv

tk-subtilisin

high-temperature

cacl2

n-propeptide

roll

hyperthermostable

Reaction

the enzyme can digest the pathological prion protein isoform (PrPSc) from different species, e.g. human, bovine, deer and mouse =

Synonyms

pernisine, subtilase, Tk-SP, Tk-subtilisin, TKS

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.B57 pernisine

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Results	in table
4	Activating Compound
2	AA Sequence
4	Application
11	Cloned(Commentary)
7	Crystallization (Commentary)
1	Expression
3	General Information
13	General Stability
28	Inhibitors
1	Ki Value [mM]
2	KM Value [mM]
5	Localization
10	Metals/Ions
14	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
13	Organic Solvent Stability
38	Organism
10	pH Optimum
4	pH Range
13	Posttranslational Modification
16	Protein Variants
9	Purification (Commentary)
1	Reaction
22	Reference
2	Specific Activity [micromol/min/mg]
36	Substrates and Products (Substrate)
12	Subunits
19	Synonyms
11	Temperature Optimum [°C]
4	Temperature Range [°C]
23	Temperature Stability [°C]
2	Turnover Number [1/s]

General Information

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General Information on EC 3.4.21.B57 - pernisine

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physiological function

Aeropyrum pernix

Q9YFI3

enzymatic degradation of protein aggregates by pernisine, such as for infective prions (PrPSc) from different origins (i.e., mouse, bovine, deer, human)

732679

additional information

2 entries