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3.4.21.74: venombin A

This is an abbreviated version!
For detailed information about venombin A, go to the full flat file.

Word Map on EC 3.4.21.74

Reaction

Selective cleavage of Arg-/- bond in fibrinogen, to form fibrin, and release fibrinopeptide A. The specificity of further degradation of fibrinogen varies with species origin of the enzyme =

Synonyms

AaV-SP-II, albofibrase1, alpha fibrinogenase, alpha-Fibrinogenase, Ancrod, Batroxobin, beta-fibrinogenase, Bhalternin, bothrombin, Bothrops atrox serine proteinase, BpirSP-39, coagulant serine protease, Crotalase, Dav-PA, EC 3.4.21.28, EC 3.4.21.29, EC 3.4.21.30, gloshedobin, Habutobin, Lachesis stenophrys venom serine proteinase, metalloproteinase 1, Mutase, acetolactate, Protein C activator, Reptilase, Russell's viper basic coagulant metalloprotease, RVBCMP, RVV protease, snake venom serine protease, TA-2, Thrombin-like enzyme, thrombin-like serine protease, TLE, Vaa serine proteinase homolog 1, VaaSPH-1, VaF1, venom gloshedobin, viper venom serine protease, VLAF, VLBF, VLCII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.74 venombin A

Molecular Weight

Molecular Weight on EC 3.4.21.74 - venombin A

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
15000
-
1 * 15000, SDS-PAGE, after reduction with beta-mercaptoethanol. 1 * 21000, SDS-PAGE, in the absence of reducing agent and heating
15090
-
MALDI-TOF-mass spectrometry
21000
-
1 * 15000, SDS-PAGE, after reduction with beta-mercaptoethanol. 1 * 21000, SDS-PAGE, in the absence of reducing agent and heating
23000
-
x * 23000, about , deglycosylated isozymes, SDS-PAGE, x * 38000, isozyme RV-FVPalpha, SDS-PAGE, x * 39000, isozyme RV-FVPbeta and isozyme RV-FVPgamma, SDS-PAGE, x* 40000, isozyme RV-FVPdelta, SDS-PAGE, x * 32901, isozyme RV-FVPalpha, mass spectrometry, x * 33363, isozyme RV-FVPbeta, mass spectrometry, x * 333571, isozyme RV-FVPgamma, mass spectrometry, x* 34594, isozyme RV-FVPdelta, mass spectrometry
27000
-
1 * 27000, SDS-PAGE
27800
-
sequence analysis
28000
-
1 * 28000, SDS-PAGE, Autographa californica nuclear polyhedrosis virus-r-habutobin
30000
30000 - 35000
-
Crotalus atrox, gel filtration
31100
31500
-
native PAGE
32000
32901
-
x * 23000, about , deglycosylated isozymes, SDS-PAGE, x * 38000, isozyme RV-FVPalpha, SDS-PAGE, x * 39000, isozyme RV-FVPbeta and isozyme RV-FVPgamma, SDS-PAGE, x* 40000, isozyme RV-FVPdelta, SDS-PAGE, x * 32901, isozyme RV-FVPalpha, mass spectrometry, x * 33363, isozyme RV-FVPbeta, mass spectrometry, x * 333571, isozyme RV-FVPgamma, mass spectrometry, x* 34594, isozyme RV-FVPdelta, mass spectrometry
33000
-
1 * 33000, Crotalus atrox, isozymes A1 and A3, SDS-PAGE
333571
-
x * 23000, about , deglycosylated isozymes, SDS-PAGE, x * 38000, isozyme RV-FVPalpha, SDS-PAGE, x * 39000, isozyme RV-FVPbeta and isozyme RV-FVPgamma, SDS-PAGE, x* 40000, isozyme RV-FVPdelta, SDS-PAGE, x * 32901, isozyme RV-FVPalpha, mass spectrometry, x * 33363, isozyme RV-FVPbeta, mass spectrometry, x * 333571, isozyme RV-FVPgamma, mass spectrometry, x* 34594, isozyme RV-FVPdelta, mass spectrometry
33363
-
x * 23000, about , deglycosylated isozymes, SDS-PAGE, x * 38000, isozyme RV-FVPalpha, SDS-PAGE, x * 39000, isozyme RV-FVPbeta and isozyme RV-FVPgamma, SDS-PAGE, x* 40000, isozyme RV-FVPdelta, SDS-PAGE, x * 32901, isozyme RV-FVPalpha, mass spectrometry, x * 33363, isozyme RV-FVPbeta, mass spectrometry, x * 333571, isozyme RV-FVPgamma, mass spectrometry, x* 34594, isozyme RV-FVPdelta, mass spectrometry
35000
-
1 * 35000, Crotalus atrox, isozyme A2, SDS-PAGE
35400
-
Agkistrodon rhodostoma, sedimentation equilibrium
36000
37000
38000
-
x * 23000, about , deglycosylated isozymes, SDS-PAGE, x * 38000, isozyme RV-FVPalpha, SDS-PAGE, x * 39000, isozyme RV-FVPbeta and isozyme RV-FVPgamma, SDS-PAGE, x* 40000, isozyme RV-FVPdelta, SDS-PAGE, x * 32901, isozyme RV-FVPalpha, mass spectrometry, x * 33363, isozyme RV-FVPbeta, mass spectrometry, x * 333571, isozyme RV-FVPgamma, mass spectrometry, x* 34594, isozyme RV-FVPdelta, mass spectrometry
38800
-
native PAGE
39000
-
x * 23000, about , deglycosylated isozymes, SDS-PAGE, x * 38000, isozyme RV-FVPalpha, SDS-PAGE, x * 39000, isozyme RV-FVPbeta and isozyme RV-FVPgamma, SDS-PAGE, x* 40000, isozyme RV-FVPdelta, SDS-PAGE, x * 32901, isozyme RV-FVPalpha, mass spectrometry, x * 33363, isozyme RV-FVPbeta, mass spectrometry, x * 333571, isozyme RV-FVPgamma, mass spectrometry, x* 34594, isozyme RV-FVPdelta, mass spectrometry
39408
-
x * 39408, mass spectrometry, x * 49000, SDS-PAGE
41500
43000
-
Bothrops marajoensis, ultracentrifugation
47900
-
1 * 47900, SDS-PAGE
49000
-
x * 39408, mass spectrometry, x * 49000, SDS-PAGE
90000
x * 90000, recombinant HusA-fusion gloshedobin, SDS-PAGE
additional information