Application | Comment | Organism |
---|---|---|
medicine | purified Autographa californica nuclear polyhedrosis virus-r-habutobin dose-dependently increases fibrin forming activity and inhibits collagen-induced aggregation of rabbit washed platelets. Thus, recombinant habutobin produced by baculoviral system is very useful for study on structure-function relationship, which is necessary for developing an antithrombotic drug from habutobin | Protobothrops flavoviridis |
Cloned (Comment) | Organism |
---|---|
pET-r-habutobin expressed in inclusion body of Escherichia coli. Autographa californica nuclear polyhedrosis virus and the habutobin/pPSC12 plasmid co-transfected into Sf9 cells | Protobothrops flavoviridis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25700 | - |
- |
Protobothrops flavoviridis |
28000 | - |
1 * 28000, SDS-PAGE, Autographa californica nuclear polyhedrosis virus-r-habutobin | Protobothrops flavoviridis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Protobothrops flavoviridis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
His-tagged recombinant habutobin fusion protein pET-r-habutobin and Autographa californica nuclear polyhedrosis virus-r-habutobin, purified by bacterial system and baculoviral system. PET-r-habutobin purified on Ni2+-NTA column | Protobothrops flavoviridis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Protobothrops flavoviridis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fibrinogen + H2O | - |
Protobothrops flavoviridis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 28000, SDS-PAGE, Autographa californica nuclear polyhedrosis virus-r-habutobin | Protobothrops flavoviridis |
Synonyms | Comment | Organism |
---|---|---|
Habutobin | - |
Protobothrops flavoviridis |