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3.4.11.20: aminopeptidase Ey

This is an abbreviated version!
For detailed information about aminopeptidase Ey, go to the full flat file.

Word Map on EC 3.4.11.20

Reaction

differs from other aminopeptidases in broad specificity for amino acids in the P1 position and the ability to hydrolyse peptides of four or five residues that contain Pro in the P1' position =

Synonyms

aminopeptidase M17, aminopeptidase N, ANPEP, APN1, Leucyl aminopeptidase, M1 aminopeptidase, M1 metalloaminopeptidase, M1-family aminopeptidase, M17 aminopeptidase, M17 leucyl aminopeptidase, malaria M1 metalloaminopeptidase, metallo-aminopeptidase M1, Pf-LAP, PfA-M1, PfA-M1 aminopeptidase, PfA-M17, Xac2987

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.20 aminopeptidase Ey

KM Value

KM Value on EC 3.4.11.20 - aminopeptidase Ey

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0236
(S)-2-amino-4-cyclohexylbutanoyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.0598
Ala-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.4 - 9
Arg-Ala
4.2 - 35
His-Ala
0.0277
homoargininyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.0262
homophenylalanyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.304
L-Ala 4-nitroanilide
pH 7.2, 37°C
0.21 - 4.4
L-alanyl-2-naphthylamide
0.27
L-Arg 4-nitroanilide
pH 7.2, 37°C
0.086 - 1.1
L-arginyl-2-naphthylamide
0.248
L-Lys 4-nitroanilide
pH 7.2, 37°C
0.0314
L-methionyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.01 - 0.8
Leu 4-methylcoumarin 7-amide
0.64 - 10
Leu-Ala
0.95
Leu-Gly
-
pH 7.5, 30°C
0.7
Leu-Gly-Gly
-
pH 7.5, 30°C
0.015
Leu-Gly-Leu
-
pH 7.5, 30°C
0.42
Leu-Gly-NH2
-
pH 7.5, 30°C
0.2
Leu-Gly-Pro
-
pH 7.5, 30°C
0.13 - 1.2
Leu-Leu
4.9
Leu-NH2
-
pH 7.5, 30°C
0.58
Leu-Pro-Leu-Arg-PheNH2
-
-
0.43 - 8.9
Lys-Ala
0.022 - 0.38
Met-Phe
0.0165
norleucyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.0354
norvalinyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
0.0302
styryl-Ala-7-amido-4-methylcoumarin
pH 7.4, 37°C