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3.4.11.20: aminopeptidase Ey

This is an abbreviated version!
For detailed information about aminopeptidase Ey, go to the full flat file.

Word Map on EC 3.4.11.20

Reaction

differs from other aminopeptidases in broad specificity for amino acids in the P1 position and the ability to hydrolyse peptides of four or five residues that contain Pro in the P1' position =

Synonyms

aminopeptidase M17, aminopeptidase N, ANPEP, APN1, Leucyl aminopeptidase, M1 aminopeptidase, M1 metalloaminopeptidase, M1-family aminopeptidase, M17 aminopeptidase, M17 leucyl aminopeptidase, malaria M1 metalloaminopeptidase, metallo-aminopeptidase M1, Pf-LAP, PfA-M1, PfA-M1 aminopeptidase, PfA-M17, Xac2987

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.20 aminopeptidase Ey

KCat KM Value

KCat KM Value on EC 3.4.11.20 - aminopeptidase Ey

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
7.6
Ala-7-amido-4-methylcoumarin
pH 7.4, 37°C
1.7 - 23
Arg-Ala
0.027 - 0.56
His-Ala
20.8
homoargininyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
31.9
homophenylalanyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
4.24
L-Ala 4-nitroanilide
pH 7.2, 37°C
3.7 - 170
L-alanyl-2-naphthylamide
5.84
L-Arg 4-nitroanilide
pH 7.2, 37°C
8.7 - 130
L-arginyl-2-naphthylamide
5.42
L-Leu 4-nitroanilide
pH 7.2, 37°C
6.24
L-Lys 4-nitroanilide
pH 7.2, 37°C
22.4
L-methionyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
1.2 - 14
Leu-Ala
6.8
Leu-Gly
-
pH 7.5, 30°C
30
Leu-Gly-Gly
-
pH 7.5, 30°C
330
Leu-Gly-Leu
-
pH 7.5, 30°C
49
Leu-Gly-NH2
-
pH 7.5, 30°C
60
Leu-Gly-Pro
-
pH 7.5, 30°C
1.2 - 97
Leu-Leu
2.4
Leu-NH2
-
pH 7.5, 30°C
3 - 65
Lys-Ala
19 - 270
Met-Phe
43
norleucyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
18.6
norvalinyl-7-amido-4-methylcoumarin
pH 7.4, 37°C
19.1
styryl-Ala-7-amido-4-methylcoumarin
pH 7.4, 37°C